Determination of right ventricular wall stress in mitral regurgitation using computer-based model

Abstract

To assess the influence of work load on both LV and RV performance in chronic severe mitral regurgitation N R ) , our model for estimating LV wall stress was extended to include the RV modeled as a hi-axially truncated prolate ellipsoid. Pressure and echocardiographic chamber dimensions were entered into the niodel. Estimated R V circurnjierential(cir), meridional(iner) and radial(racl) stress in AdR were 124+13, 97*13 and 1612, and LV cir, mer and rad stress estimates were 300h31, 123*14 and 68+5 (xl d Dynes/cm?, respectively. The RV-cir and rad and LV-cir, mer and rad stresses were signiJicantly higher than control(p<. 05). These preliminary results indicate that RV wall stress estimation appears feasible and niay provide important pathophysiologic understanding of processes aflecting both R 17 and L Vperforniance.