Determination of proteoglycan dimer geometry by electric birefringence

Trimm, Harold H.; Jennings, B. R.

doi:10.1016/0141-8130(82)90072-1

Cited by 1 publication

(1 citation statement)

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“…Several important biopolymers present a typical brokenrod conformation in which two rodlike arms are joined either rigidly or by means of a flexible hinge or swivel. A well-known example is myosin rod (Harvey and Cheung, 1982;Trybus et al, 1982), and other relevant cases include fibronectin (Odermatt et al, 1982), proteoglycan (Trimm and Jennings, 1982) and, in some regard, DNA (Hagerman, 1984). For rigid bent rods, the hydrodynamic properties can be obtained using the theory of rigid particles (Garcia de la Torre, 1981; Garcia Bernal and Garcia de la Torre, 1980;Garcia de la Torre andBloomfield, 1978, 1981).…”

Section: Introductionmentioning

confidence: 99%

Transport properties of rigid bent-rod macromolecules and of semiflexible broken rods in the rigid-body treatment. Analysis of the flexibility of myosin rod

Iniesta¹,

Díaz²,

Torre³

1988

Biophysical Journal

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The translational diffusion coefficients, rotational relaxation times and intrinsic viscosities of rigid bent rods, composed by two rodlike arms joined rigidly at an angle alpha, have been evaluated for varying conformation using the latest advances in hydrodynamic theory. We have considered semiflexible rods in which the joint is an elastic hinge or swivel, with a potential V(alpha) = 1/2Q alpha 2 with constant Q. Accepting the rigid-body treatment, we calculate properties of broken rods by averaging alpha-dependent values for rigid rods. The results are finally used to interpret literature values of the properties of myosin rod. Q is regarded as an adjustable parameter, and the value fitted is such that the average bending angle of myosin rod is approximately 60 degrees.

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