Abstract:Background: ALPPS (associating liver partition and portal vein ligation for staged hepatectomy) is a two-stage strategy to induce rapid hypertrophy of future liver remnant (FLR) to increase hepatic tumor resectability and reduce postoperative liver failure rate. Rigorous and accurate determination of the pathophysiological mechanisms involved in hypertrophy of FLR in ALPPS is essential to ensure a good success rate in the second stage operation. Methods: An ALPPS model was established in rabbits with liver VX2… Show more
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