Determination of NO production in melanoma cells using an amperometric nitric oxide sensor

Ab initio molecular dynamics simulation of aqueous solution of nitric oxide in different formal oxidation states

“…Currently, several studies have been focused in obtaining stable transition metal compounds for the in situ delivery of NO, in a controlled manner, upon chemical [11][12][13], electrochemical [14] or photochemical [15][16][17][18][19][20] stimuli in the organism. Of particular interest are the compounds that can deliver NO upon light irradiation aiming at a more effective targeting.…”

ATR-FTIR Spectroscopy of Membrane Bound Ras Protein

“…Complexity in the biological media needs to be resolved with the combined model systems; therefore, several NO detection methods have been proposed [160][161][162][163][164][165][166][167][168][169][170][171][172][147][148][149]. Its production in vast amounts by white blood cells to combat infectious bacteria and parasites, lead to the initial realization of controlled NO release as a prospective strategy against cancer.…”

Electrochemical metallization of self-assembled porphyrin monolayers

“…Self-assembling Ni-porphyrin monolayers are an interesting approach in electroanalytical chemistry, because Niporphyrins are described as NO sensors by many authors [9,10,11,12,17]. The self-assembly of Ni-porphyrins on gold is extremely difficult -almost impossible -because of the strong affinity of nickel for sulfur.…”

“…Electrochemical detection of NO is usually (and commercially) performed amperometrically with Ni-porphyrin-modified glassy carbon electrodes [9,10,11,12]. The objective of this research was, therefore, to create a similar NO-sensor, in planar technology, by application of a microstructurable self-assembled Ni-porphyrin monolayer on a gold substrate.…”