2010
DOI: 10.1016/j.foodchem.2010.05.018
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Determination of nitrofurans residues in animal feeds by flow injection chemiluminescence procedure

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Cited by 42 publications
(20 citation statements)
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“…Due to the potentially carcinogenic and mutagenic effects of their metabolites on human health (Copper et al, 2007), use of nitrofurans in food-producing animals has been prohibited within the European Union (EU) for more than a decade. Because of the very short elimination half-lives of nitrofurans, it is almost impossible to detect any residues of parent compounds in edible tissues after administration for some hours (Thongsrisomboon, Liawruangrath, Liawruangrath & Satienperakul, 2010). But a concomitant accumulation of their tissue-bound residues can be observed.…”
Section: Introductionmentioning
confidence: 99%
“…Due to the potentially carcinogenic and mutagenic effects of their metabolites on human health (Copper et al, 2007), use of nitrofurans in food-producing animals has been prohibited within the European Union (EU) for more than a decade. Because of the very short elimination half-lives of nitrofurans, it is almost impossible to detect any residues of parent compounds in edible tissues after administration for some hours (Thongsrisomboon, Liawruangrath, Liawruangrath & Satienperakul, 2010). But a concomitant accumulation of their tissue-bound residues can be observed.…”
Section: Introductionmentioning
confidence: 99%
“…The SPE method was similar to that described previously (Thongsrisomboon et al, 2010); however, the evaporated residue was reconstituted with 5 mL of 0.11 M PBS instead of a H 2 SO 4 carrier solution. The results of the NF measurements were comparative to the HPLC procedure with photodiode-array detection (Barbosa et al, 2007), used as a reference method, as can be seen in Table 3.…”
Section: Analytical Characteristics and Application To Real Samplesmentioning
confidence: 99%
“…TheArgentinean legislation established levels of nitrofurans in animal feed at maximum limits of 400 µg kg -1 , and 2 µg L -1 in water for poultry for the compounds NFZ, FTD, FZD and NFT(Viñas et al 2007). So far, only three reports were found proposing the determination of NFs 4 in various samples Thongsrisomboon et al (2010). have recently reported a flow injection CL method for the determination of FZD, NFT and NFZ in animal feed, based on chemiluminescence induced by potassium permanganate in a sulfuric acid medium with detection limits (S/N = 3) of 0.25 mg L -1 , and a sample throughput of 120 h -1 Du et al (2007).…”
mentioning
confidence: 99%
“…Nitrofuranzone (NFZ) as a low-cost and high-efficiency broad spectrum of antimicrobial agents of nitrofurans is widely used for the treatment of gastrointestinal and dermatological infections in animal husbandry and aquaculture [6]. However, the overuse and misuse of them have led to adverse environmental effects and antibiotics resistance transfer to human pathogenic microbes [7][8][9][10][11][12].…”
Section: Introductionmentioning
confidence: 99%