Determination of methyl methacrylate in surgical acrylic cement

Sheinin, Eric B.; Benson, Walter R.; Brannon, Wilson L

doi:10.1002/jps.2600650225

Cited by 10 publications

(3 citation statements)

References 2 publications

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“…24 The residual monomer in the cured cement was measured after 1 h of polymerization at 37°C by means of 1 H-NMR spectroscopy. 25 The NMR spectra were recorded in a Varian VXR-300 spectrometer operating at 75.5 MHz at room temperature. The samples were dissolved using chloroform-d 1 and pyridine-d 6 as solvents and tetramethylsilane (TMS) as the internal reference.…”

Section: Residual Monomer Contentmentioning

confidence: 99%

Characterization of new acrylic bone cement based on methyl methacrylate/1-hydroxypropyl methacrylate monomer

Pascual

Goñi

Gurruchaga

1999

J. Biomed. Mater. Res.

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New formulations of acrylic bone cement based on methyl methacrylate/1-hydroxypropyl methacrylate (MMA/HPMA) monomers were developed with the purpose of obtaining more ductile materials with reduced polymerization shrinkage. In this way, the ductility of such materials increased, but the introduction of high percentages of the hydrophilic component produced an important decrease in Young's modulus and strength. To ascertain the reason for the deterioration of the tensile parameters, an analysis by scanning electron microscopy of these formulations was carried out; it revealed poor adhesion between the matrix and poly(MMA) beads. We also observed that the polymerization shrinkage increased as the amount of hydrophilic monomer in the formulation decreased, and the 50% (v/v) HPMA modified bone cement compensated for this volume reduction with its water uptake swelling. Measurements taken on the setting time and polymerization exotherm showed a decrease in the former and an increase in the latter, because of the introduction of a more reactive monomer in the bone cement formulation.

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Section: Residual Monomer Contentmentioning

confidence: 99%

Characterization of new acrylic bone cement based on methyl methacrylate/1-hydroxypropyl methacrylate monomer

Pascual

Goñi

Gurruchaga

1999

J. Biomed. Mater. Res.

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“…The main portion of acrylates are disposed to seas and rivers along with the separated produced water, which can be absorbed through the skin, causing nervous system symptoms and cancers in human as well as death of the animals [1,2]. The available analytical methods, used for acrylates, are mainly based upon chromatography and spectroscopy, including gas chromatography (GC) [3,4], high performance liquid chromatography (HPLC) [5,6], proton nuclear magnetic resonance ( 1 H NMR) spectroscopy [7], refractive indices [8] etc.…”

Section: Introductionmentioning

confidence: 99%

Determination of Acrylates in Wastewater by Dispersive Liquid-Liquid Microextraction Coupled to Capillary Gas Chromatography

Sun

Zeng

Liu

2014

AMR

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This study describes an analytical method employing capillary gas chromatography (GC) using flame ionization detection (FID) that has been developed for the simultaneous determination of acrylates (methyl acrylate (MA), methyl methacrylate (MMA), butyl acrylate (BA)) in wastewater. For this purpose, dispersive liquid-liquid microextraction (DLLME) was applied as a sample preparation technique. The DLLME conditions such as the types and volume of extraction solvent, the types and volume of the disperser solvent, pH value and salt addition were studied and optimized. The method was linear in the ranges from 4.3×10-4 to 200.0 μg·mL-1 for abovementioned acrylates with R2≥ 0.9992. The DLLME procedure allowed efficient recovery of the investigated acrylates ranging between 81 % and 109 % with a relative standard deviation (RSD) ≤ 9.1 for the blank samples spiked with 10, 50 and 100 μg·mL-1 of acrylates, respectively. These results showed the potential of this technique for acrylates monitoring in wastewater samples. Furthermore, the investigated methods are simple, reproducible, and inexpensive.

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“…Therefore, it is justified to assume that the majority of monomer loss from the cement during the process of polymerization occurs via evaporation. After hardening, residual monomer remains within the polymerized matrix, but only small quantities still reach the surrounding tissue 1, 10–12. The released monomer has major health effects, and might contribute to implant loosing and failure.…”

Section: Introductionmentioning

confidence: 99%

Quantitative analysis of monomer vapor release from two‐solution bone cement by using a novel FTIR technique

2005

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Methyl methacrylate monomer can evaporate from bone cement to reach cytotoxic levels of concentrations in the implant bed of total joint prosthesis. Therefore, this study was performed by using a novel Fourier transform infrared spectroscopy method to quantify the release of monomer vapor from experimental two-solution bone cement in vitro during polymerization, to examine the effect of surface area versus cement mass, and to explore the effect of initiation chemistry. The results revealed that monomer vapor release is a surface phenomenon. In addition, initiation chemistry plays a major role in controlling the reaction time, and therefore heat concentration and dissipation, which resulted in a higher absorbance peak as initiation chemicals concentration increased. It was concluded that using the FTIR to monitor MMA vapors is an effective technique to obtain quantitative information about monomer vapor release from bone cements during polymerization and provides insight on the polymerization kinetics of two-solution acrylic bone cement.

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Determination of methyl methacrylate in surgical acrylic cement

Cited by 10 publications

References 2 publications

Characterization of new acrylic bone cement based on methyl methacrylate/1-hydroxypropyl methacrylate monomer

Characterization of new acrylic bone cement based on methyl methacrylate/1-hydroxypropyl methacrylate monomer

Determination of Acrylates in Wastewater by Dispersive Liquid-Liquid Microextraction Coupled to Capillary Gas Chromatography

Quantitative analysis of monomer vapor release from two‐solution bone cement by using a novel FTIR technique

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