Determination of methenamine residues in edible animal tissues by HPLC-MS/MS using a modified QuEChERS method: Validation and pilot survey in actual samples

Core–Shell Au@Metal–Organic Frameworks for Promoting Raman Detection Sensitivity of Methenamine

“…At present, the routine methods for the detection of methenamine are ion chromatography, gas chromatography (GC)–mass spectrometry (MS), high-performance liquid chromatography (HPLC)–MS/MS, ultraperformance liquid chromatography (UPLC)–MS–MS, , and UV–vis spectrophotometry . For instance, in the national standard (GB/T23296.26-2009), UV–vis spectrophotometry is recommended to determine methenamine via formation of formaldehyde from methenamine in an acidic medium .…”

“…Abuse of methenamine leads to the damage of the kidney, liver, nervous system, immune system, and digestive system because it will produce formaldehyde and methanol in the human body. 1,2 At present, the routine methods for the detection of methenamine are ion chromatography, 1 gas chromatography (GC)−mass spectrometry (MS), 3 high-performance liquid chromatography (HPLC)−MS/MS, 4 ultraperformance liquid chromatography (UPLC)−MS−MS, 5,6 and UV−vis spectrophotometry. 7 For instance, in the national standard (GB/ T23296.…”

3DG Functionalized Magnetic Solid Phase Extraction Materials for the Efficient Enrichment of Hexamethylenetetramine in Vermicelli

“…Molecules 2022, 27, 1548 2 of 13 Presently, the commonly used methods for detection of HMT include spectrophotometry [10], chromatography [11], Raman spectroscopy [12], and high-performance liquid chromatography/tandem mass spectrometry method (HPLC-MS/MS) [13]. However, detection of trace components directly from a complex matrix by these methods is difficult.…”

“…However, detection of trace components directly from a complex matrix by these methods is difficult. Hence, these methods of analysis require suitable sample pretreatments, such as the QuEChERS method [ 13 ] and SPE method [ 14 , 15 ]. These methods are often time-consuming, complicated, and usually coupled with expensive mass spectrometric techniques requiring isotopic labeling.…”

Rapid detection of hexamethylenetetramine based on the substrate UC@SiO2@Au@Ag using SERS

“…1 Up till now, the various modern methods used to detect HMT have been gas chromatography coupled mass spectrometry (GC-MS) 2,3 and high performance liquid chromatography coupled with tandem mass spectrometry (HPLC-MS/MS). 4 Although these methods are accurate, reliable and sensitive, they are time consuming, expensive and labour-intensive. 5 Therefore, an advanced method that is rapid, has a simple operation and is inexpensive is crucial to detect HMT in food products.…”