Abstract:The mesenchymal cell is a multipotent stem cell with the capacity to give rise to multiple cell types.Recently, a number of studies have demonstrated a role of BMP4 in the commitment of mesenchymal stem cells (C3H10T1/2) into the adipocyte lineage. Previously we investigated the genetic events underlying adipocyte commitment, for which C3H10T1/2 stem cells were treated with 5‐azaC and selected preadipocyte clonal lines, named A33 line. In this study, we analyzed the BMP4 promoter region in 10T1/2 and A33 cell.… Show more
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