Determination of Mercury and Selenium in Biological Samples by Neutron Activation Analysis

Vasconcellos, M. B. A.; Catharino, M. G. M.; Paletti, G.; Saiki, M.; Bode, P.; Fávaro, D. I. T.; Baruzzi, Roberto Geraldo; Rodrigues, Diego de Macedo

doi:10.1081/tma-120015614

Cited by 10 publications

(9 citation statements)

References 4 publications

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“…For total elemental analysis, neutron activation analysis of selenium and mercury has been shown in several types of biological samples such as hair, nails, fish reference materials, porcupine tissues and also in selenium supplements. 15,16 However, subcellular fractions must be collected and off-line analysis is required if chromatography is necessary. Total concentrations of selenium and mercury have been successfully determined by atomic absorption spectrometry and inductively coupled plasma mass spectrometry (ICPMS) with detection limits in the low mg l À1 range.…”

Section: Introductionmentioning

confidence: 99%

The effect of Se antagonism on the metabolic fate of Hg in Allium fistulosum

Afton

Caruso

2009

J. Anal. At. Spectrom.

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Section: Introductionmentioning

confidence: 99%

The effect of Se antagonism on the metabolic fate of Hg in Allium fistulosum

Afton

Caruso

2009

J. Anal. At. Spectrom.

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“…Each Hg 2+ standard solution was standardized using a prompt γ "Neutron Activation Analysis" (NAA) instrumentation (14-MeV, Ordela model 4511 N neutron detector, OPAL, Australia) based on a reference procedure. 15 For this purpose, briefly, 10.0 mL of the aqueous solution containing a fresh Hg 2+ solution at the sub nM concentration level was introduced into the NAA system as the standard method. During the bombardment of the liquid sample with the neutrons (neutron flux: 1 × 10 13 n cm −2 s −1 , kinetic energy: 2.0 keV, reaction, 200 Hg (n, p) 200 Au, E γ (MeV): 0.367−0.36, half-life: 48.0 min), the radioactive emissions (i.e., the emitted γ radiation), as well as the radioactive decay paths for each element, were detected and measured using a gas ionization detector, thereby measuring the concentration of the Hg 2+ standard solutions.…”

Section: Neutron Activation Analysismentioning

confidence: 99%

In Vivo Chemogenetic Biocompatibility of Mercury as a Specific Hypercalcemia Actuator in Snail’s Spinal Cord Cell Manipulation: An Extracellular Field Potential Biosensor

Karami

Doroodmand

Mootabi-Alavi

2022

ACS Appl. Bio Mater.

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The in vivo chemogenetic property of mercuric ions (Hg2+) was investigated as a specific hypercalcemia actuator in snail’s spinal cord cell manipulation by extracellular field potential biosensing analysis. For this purpose, a three-microelectrode system with working, counter, and pseudo reference electrodes was blindly implanted into the snail’s spinal cord to electrically stimulate (triggering) the action potential with a staircase electrical voltage at a very low frequency level, along with measurement of the electrical current, as a detection system. Under optimum conditions, using the one-factor-at-a-time method, a wide linear range between 1.0 × 10–14 and 1.0 × 10–1 mol L–1 with correlation coefficients (R 2) >0.98 and a response time (t 90) of maximum 10.0 s were approximated. Percentages of relative standard deviation were estimated to be 3.08 (reproducibility, n = 50) and 7.31 (repeatability, n = 15). The detection limit was estimated to be sub 2.1 × 10–16 mol L–1 based on the Xb – + 3Sb definition. The reliability of this phenomenon was evidenced by the estimation of recovery percentages (between 95 and 107%) during spiking Hg2+ standard solutions. The probable mechanism behind this process could be attributed to the following: (i) the neuronal ephaptic coupling during electrical synchronization by a specific brain-triggered wave as a neuronal motor toolkit and (ii) chemical synchronization using a Hg2+ hypercalcemia actuator (biosensor). Linear correlation has been evidenced during interactions between Hg2+ and a calcium ionic channel’s protein with a gram molecular weight of 66.2 ± 0.3 KCU. This process, therefore, caused an opening of the Ca2+ channel gates and majorly released the Ca2+ (hypercalcemia) that was detected as the main source of the measured electrical current. At this condition, ultratrace levels of Hg2+ ions not only were considered as nontoxic reagents but also had chemically regulating effects as ephaptic synchronizers to the neuron cells. This report may pave the way for using mercury ions at an ultratrace level for clinical controlling purposes during neuronal spinal cord cell manipulation.

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“…Accurate determination of platinum group metals (PGMs) is a major issue and many laboratories around the world are adding chemicals to the sample in order to be suitable for analysis. The determination of PGMs needs highly sensitive and selective techniques such as inductively coupled plasma mass spectrometry (ICP‐MS) , inductively coupled plasma atomic emission spectroscopy (ICP‐AES) , atomic absorption spectrometry (AAS) , neutron activation analysis (NAA) , or thermal ionization mass spectrometry (TIMS) , and X‐ray fluorescence spectrometry . ICP‐MS is characterized by rapidity, simplicity and multi‐elementary capacity, although isobaric interferences – like 63 Cu 40 Ar + or 91 Zr 12 C + or 103 Rh ‐ may cause severe inaccuracies in the determination of PGMs , more noteworthy at the ultratrace level PGMs concentrations of biological or environmental samples.…”

Section: Introductionmentioning

confidence: 99%

Reduced Graphene Oxide Impregnated Antimony Nanoparticle Sensor for Electroanalysis of Platinum Group Metals

et al. 2016

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A very sensitive electrochemical sensor based on a reduced graphene oxide film impregnated with antimony nanoparticles was prepared and applied to the electroanalysis of platinum group metal ions of Pd(II), Pt(II) and Rh(III). The electrochemical behavior of platinum group metals at the modified electrode was studied by adsorptive differential pulse cathodic stripping voltammetry in the presence of dimethylglyoxime as chelating agent. Several operational parameters were optimised to enhance the electroanalytical performance of the modified glassy carbon electrode sensor. The results showed sharp stripping peaks and a relatively constant peak potential with a good linear behaviour in the examined concentration range from 40 to 400 pg L−1 for all metal ions investigated. The detection limit was found to be 0.45, 0.49 and 0.49 pg L−1 (S/N=3) for Pd(II), Pt(II) and Rh(III), respectively. The developed electrochemical sensor also exhibited good precision with a relative standard deviation of 4.2 %, 2.55 % and 2.67 % for 5 successive measurements for Pd(II), Pt(II) and Rh(III), respectively. The proposed nanostructure showed good sensitivity and stability, which has promising potential applications in electrochemical sensors.

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Determination of Mercury and Selenium in Biological Samples by Neutron Activation Analysis

Cited by 10 publications

References 4 publications

The effect of Se antagonism on the metabolic fate of Hg in Allium fistulosum

The effect of Se antagonism on the metabolic fate of Hg in Allium fistulosum

In Vivo Chemogenetic Biocompatibility of Mercury as a Specific Hypercalcemia Actuator in Snail’s Spinal Cord Cell Manipulation: An Extracellular Field Potential Biosensor

Reduced Graphene Oxide Impregnated Antimony Nanoparticle Sensor for Electroanalysis of Platinum Group Metals

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