Determination of melamine residues in milk products by zirconia hollow fiber sorptive microextraction and gas chromatography–mass spectrometry

Li, Jia; Qi, Huanhuan; Shi, Yan‐Ping

doi:10.1016/j.chroma.2009.05.047

Cited by 151 publications

(73 citation statements)

References 17 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Various techniques including HPLC-UV [10][11][12] or hydrophilic interaction liquid chromatography (HILIC)-UV [13], HPLC-MS [14][15][16][17][18][19][20][21][22][23][24], GC-MS [24][25][26], desorption ionization MS [27], CE [28][29][30], electrochemical method [31], etc., have been used to detect melamine or cyanuric acid. For the simultaneous determination of melamine and cyanuric acid, HPLC-MS [32] and MALDI-MS [33] were employed.…”

Section: Introductionmentioning

confidence: 99%

Simultaneous determination of melamine and related compounds by hydrophilic interaction liquid chromatography–electrospray mass spectrometry

Xia

Zhou

et al. 2010

J of Separation Science

View full text Add to dashboard Cite

Simultaneous determination of melamine and related compounds by hydrophilic interaction liquid chromatographyelectrospray mass spectrometryA hydrophilic interaction liquid chromatography coupled to ESI-MS (HILIC/ESI-MS) method for the simultaneous determination of melamine and related compounds, i.e. ammeline, ammelide and cyanuric acid in foods was developed and validated. The separation was accomplished on a Venusil HILIC column with a mobile phase of acetonitrile 1 10 mM ammonium formate buffer solution at pH 3.5 (88:12, v/v) under isocratic elution mode. For the detection of the targets, the ESI probe worked in the positive and negative switching mode. For each compound, three ions were selected as qualitative ions to obtain high specificity, and the most abundant ion of each compound was selected for quantification to obtain high sensitivity. The target compounds were quantified using SIM with 15N3-melamine and 13C3-cyanuric acid being used as an internal standards in the positive and negative modes, respectively. Compared with RP separation mode, HILIC has merits such as high separation and anti-interference efficiency. The method validation including linearity, LOD, LOQ, precision and recovery proved that the method has merits such high sensitivity, specificity and simplicity versus the other methods reported in the literature.

show abstract

Section: Introductionmentioning

confidence: 99%

Simultaneous determination of melamine and related compounds by hydrophilic interaction liquid chromatography–electrospray mass spectrometry

Xia

Zhou

et al. 2010

J of Separation Science

View full text Add to dashboard Cite

show abstract

“…The US FDA had developed a GC-MS method for analyzing melamine and its analogs in various matrices such as wet and dry animal food, wheat, corn gluten, rice, soy protein, health drink formulas and dietary supplements (http://www.fda.gov/Food/ScienceResearch/ LaboratoryMethods/DrugChemicalResiduesMethodology/ ucm071759.htm (accessed 7th July 2010)). Other laboratories had also used GC-MS to analyze melamine in animal feed [18], dairy products [19][20][21], eggs [22] and meat [23]. Another method of analysis is GC-MS/MS ( [24][25][26][27] 2011)).…”

Section: Introductionmentioning

confidence: 99%

Determination of melamine in milk powder using gas chromatography–high‐resolution isotope dilution mass spectrometry

Koh

Chia

Lin

et al. 2011

J of Separation Science

View full text Add to dashboard Cite

A GC-high-resolution isotope dilution MS (IDMS) method for the quantification of melamine in milk powder is described. The developed technique is compared to the LC-IDMS/MS technique, typically used for the determination of melamine in various matrices. The accuracy of the GC-high-resolution IDMS method was demonstrated when a small degree of equivalence was obtained in a regional comparative study involving the determination of melamine in milk powder.

show abstract

“…Therefore, the growing concern over tainted milk products requires a simple and effective method for the analysis of MM in these products. Various methods including GC [4][5][6], LC [6][7][8][9][10][11][12][13][14][15], CE [16][17][18][19][20][21][22][23], ultraviolet-visible spectroscopy (UVVis) [24], ELISA [25], infrared spectroscopy [26], surfaceenhanced Raman spectroscopy [8,27] and MS [28][29][30][31], and even colorimetry [24,32] have been developed for the detection of MM in various matrices in recent years.…”

Section: Introductionmentioning

confidence: 99%

Highly sensitive detection of melamine and its derivatives by capillary electrophoresis coupled with online preconcentration techniques

Jin

Meng

et al. 2010

Electrophoresis

View full text Add to dashboard Cite

Two kinds of online preconcentration techniques including large-volume sample stacking-sweeping and selective-exhaustive injection-sweeping (SEI-S) were employed in CE to develop a rapid, simple and sensitive method for determination of melamine (MM) and its derivatives such as ammeline (AMN), ammelide (AMD) and cyanuric acid (CA) in liquid milk products. Though the sensitivity of large-volume sample stacking-sweeping is not particularly high, it can be used to detect all the four compounds simultaneously. However, it is very difficult to improve the sensitivity of these four compounds by using single SEI-S method directly, owing to their completely different extents of protonation or deprotonation. Grouping can solve this problem perfectly. After the four compounds are divided into two groups (MM/AMN and AMD/CA), cation-SEI-S or anion-SEI-S can be applied for their online stacking. In cation-SEI-S, the detection limits for MM and AMN were both 0.01 ng/mL based on the signal-to-noise ratio of 3. In anion-SEI-S, the detection limits were 0.05 and 0.02 ng/mL for CA and AMD, respectively. Results of this study show a great potential for the SEI-S method to be a useful tool for the rapid and sensitive determination of MM and its derivatives in liquid milk products.

show abstract

Determination of melamine residues in milk products by zirconia hollow fiber sorptive microextraction and gas chromatography–mass spectrometry

Cited by 151 publications

References 17 publications

Simultaneous determination of melamine and related compounds by hydrophilic interaction liquid chromatography–electrospray mass spectrometry

Simultaneous determination of melamine and related compounds by hydrophilic interaction liquid chromatography–electrospray mass spectrometry

Determination of melamine in milk powder using gas chromatography–high‐resolution isotope dilution mass spectrometry

Highly sensitive detection of melamine and its derivatives by capillary electrophoresis coupled with online preconcentration techniques

Contact Info

Product

Resources

About