Determination of maleic hydrazide residues in garlic bulbs by HPLC

Moreno, Claudia Mariela Mamani; Stadler, Teodoro; Silva, Antônio Alberto da; Barbosa, Liuz C. A.; Queiroz, Maria Eliana Lopes Ribeiro de

doi:10.1016/j.talanta.2011.12.045

Cited by 32 publications

(7 citation statements)

References 44 publications

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“…This prevented the analytical column from being fouled with nonpolar compounds. MH has a slight retention in reversed-phase mode, and it may be partially retained on the Oasis HLB cartridge during the cleanup step with acid/Na 2 EDTA solution. The elution profile of each standard was tested by passing a standard mix solution in acetic/Na 2 EDTA solution through an Oasis HLB cartridge and determining the recovery for each compound.…”

Section: Resultsmentioning

confidence: 99%

“…Kubilius and Bushway developed a capillary electrophoresis technique to determine MH in potato and onion at a 2–20 μg/g level . Moreno et al (2012) developed an HPLC-UV method and confirmation with MS using the atmospheric pressure chemical ionization (APCI) interface to determine MH residue in garlic bulbs . According to 40CFR180.175, MH has tolerance only in potato and onion at 50 and 15 μg/g and no tolerance in grapes…”

Section: Introductionmentioning

confidence: 99%

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Determination of Glyphosate, Maleic Hydrazide, Fosetyl Aluminum, and Ethephon in Grapes by Liquid Chromatography/Tandem Mass Spectrometry

Chamkasem

2017

J. Agric. Food Chem.

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A simple high-throughput liquid chromatography/tandem mass spectrometry (LC-MS-MS) method was developed for the determination of maleic hydrazide, glyphosate, fosetyl aluminum, and ethephon in grapes using a reversed-phase column with weak anion-exchange and cation-exchange mixed mode. A 5 g test portion was shaken with 50 mM HOAc and 10 mM NaEDTA in 1/3 (v/v) MeOH/HO for 10 min. After centrifugation, the extract was passed through an Oasis HLB cartridge to retain suspended particulates and nonpolar interferences. The final solution was injected and directly analyzed in 17 min by LC-MS-MS. Two MS-MS transitions were monitored in the method for each target compound to achieve true positive identification. Four isotopically labeled internal standards corresponding to each analyte were used to correct for matrix suppression effects and/or instrument signal drift. The linearity of the detector response was demonstrated in the range from 10 to 1000 ng/mL for each analyte with a coefficient of determination (R) of ≥0.995. The average recovery for all analytes at 100, 500, and 2000 ng/g (n = 5) ranged from 87 to 111%, with a relative standard deviation of less than 17%. The estimated LOQs for maleic hydrazide, glyphosate, fosetyl-Al, and ethephon were 38, 19, 29, and 34 ng/g, respectively.

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Section: Resultsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Determination of Glyphosate, Maleic Hydrazide, Fosetyl Aluminum, and Ethephon in Grapes by Liquid Chromatography/Tandem Mass Spectrometry

Chamkasem

2017

J. Agric. Food Chem.

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“…Several techniques have been explored for detecting HZ including spectrophotometry, chromatography, colorimetry, titrimetry, potentiometry, chemiluminescence, electrochemical method, and chemiresistive sensors. − Among all the techniques for the detection of HZ, the chemiresistive sensor has garnered high intertest because of its high sensitivity, fast response, low cost, simplicity, and suitability for real-time detection. ,− Chemiresistive sensors have achieved notable sensor success criteria utilizing the electrochemical deposition of nanomaterials on top of microelectronic devices (MEDs). ,, Sensor achievements include effective response, recovery, and some selectivity . These nanomaterial-based chemiresistive sensors trap gas molecules and signal a voltage response that correlates to a concentration of gas. − However, the process of fabricating these sensors including nanomaterials’ implementation has been very difficult, expensive, and time consuming. ,, In addition, current chemiresistive sensors lack selectivity and reusability.…”

Section: Introductionmentioning

confidence: 99%

Selective and Trace Level Detection of Hydrazine Using Functionalized Single-Walled Carbon Nanotube-Based Microelectronic Devices

Kweon

Hosking

Mushfiq

et al. 2021

ACS Appl. Electron. Mater.

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Microelectronic devices (MEDs) that utilize functionalized single-walled carbon nanotubes (SWCNTs) for hydrazine (HZ) sensing applications were developed and investigated, demonstrating their selective and sensitive detection of trace level HZ (0.01 ppm) in the presence of high-concentration interfering gases in ambient air at room temperature. These MEDs were fabricated with excellent reproducibility by the site-specific deposition of functionalized SWCNTs using a dielectrophoretic technique. Rigorous gas exposure testing conducted on these MEDs demonstrated a fast response with high sensitivity, selectivity, reproducibility, and reliability for detecting HZ. A dynamic response range was established from a linear relationship between the sensor response and the concentration of HZ (0.01 to 0.33 ppm). Additionally, these MEDs exhibited a linear trend relationship between device resistance and sensor response, which provided tunability in selecting and fabricating devices for improving sensing response. Field-emission scanning electron microscopy images showed the morphology of SWCNTs as a bundle on MEDs. Additional analytic gas exposure tests revealed negligible responses from these MEDs for high concentrations of interfering gases, such as 300 ± 17 ppm methanol (MeOH), 85 ± 6 ppm ethanol (EtOH), 145 ± 12 ppm formaldehyde (CH2O), and 500 ppm ammonia (NH3), compared to that of HZ (≤0.33 ppm), with HZ to interfering gas concentration ratios of 1:900, 1:250, 1:440, and 1:1500, respectively, demonstrating high sensor selectivity for HZ.

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“…Various techniques have been established for the determination of MH, including colorimetric methods, chromatographic methods, electrochemical methods, etc. Among them, as the powerful separation technique, chromatographic methods are the most widely employed approaches for MH analysis in different matrices such as garlic, potato, and tobacco.…”

Section: Introductionmentioning

confidence: 99%

“…In GC based methods, the extracted MH residues in tobacco were firstly derivatized with either N,O ‐bis(trimethylsilyl) acetamide or dimethyl sulfate, and the obtained MH derivatives were measured by GC coupled with flame ionization detector or GC coupled with nitrogen‐phosphorus detector. In HPLC based methods, MH residues were usually extracted with methanol or HCl by multiple partition steps, and finally analyzed using HPLC with UV detector at wavelengths ranged from 303 to 330 nm. In recent years, with the advancement of instrumentation, LC–MS/MS based methods have been established for determination of MH only or MH and other pesticides simultaneously …”

Section: Introductionmentioning

confidence: 99%

Use of autoclave extraction and liquid chromatography with tandem mass spectrometry for determination of maleic hydrazide residues in tobacco

Deng

Bian

Yang

et al. 2019

J of Separation Science

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Maleic hydrazide has been extensively used as an effective growth regulator in tobacco sucker control. After application, maleic hydrazide distributes itself throughout the tobacco plant where it can exist as free, or forms glucoside conjugates with glucose, or becomes bound with lignin. Among them, free maleic hydrazide and its glucoside conjugates are extractable under conventional solvent extraction, while lignin bound maleic hydrazide is claimed to be non-extractable. Herein, an autoclave extraction method has been developed to extract maleic hydrazide effectively, in which tobacco samples are extracted in an autoclave at 130 • C for 1 h using 4 M hydrochloric acid.Under such pressurized hot acidic water conditions, lignin bound maleic hydrazide can be released. Meanwhile, glucoside conjugates are hydrolyzed. Total maleic hydrazide is detected by liquid chromatography coupled with tandem mass spectrometry, and the quantitative results coincide well with that obtained from the international standard method. The proposed autoclave extraction with liquid chromatography and tandem mass spectrometry method exhibits excellent linearity in the range of 5-200 mg/kg (R 2 = 0.9998), the matrix matched limit of detection and limit of quantification is 0.68 and 2.27 mg/kg, respectively. This method is simple and improves sample capacity, providing an effective approach to monitoring maleic hydrazide residues in tobacco. K E Y W O R D Sautoclave extraction, liquid chromatography, maleic hydrazide, tandem mass spectrometry, tobacco 2390

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Determination of maleic hydrazide residues in garlic bulbs by HPLC

Cited by 32 publications

References 44 publications

Determination of Glyphosate, Maleic Hydrazide, Fosetyl Aluminum, and Ethephon in Grapes by Liquid Chromatography/Tandem Mass Spectrometry

Determination of Glyphosate, Maleic Hydrazide, Fosetyl Aluminum, and Ethephon in Grapes by Liquid Chromatography/Tandem Mass Spectrometry

Selective and Trace Level Detection of Hydrazine Using Functionalized Single-Walled Carbon Nanotube-Based Microelectronic Devices

Use of autoclave extraction and liquid chromatography with tandem mass spectrometry for determination of maleic hydrazide residues in tobacco

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