Determination of macrolides in animal tissues and egg by multi-walled carbon nanotube-based dispersive solid-phase extraction and ultra-high performance liquid chromatography–tandem mass spectrometry

Developing a novel magnetic organic polymer for selective extraction and determination of 16 macrolides in water and honey samples

“…Effect of sample solution pH. MALs are weakly basic compounds, and their glycosidic bonds are easily hydrolyzed under acidic conditions (pH < 4) and cracked central rings under alkaline conditions (pH > 9), 51 which affects the extraction efficiency. By adding an appropriate amount of formic acid or ammonia, the adsorption of MALs was investigated Fe 3 -O 4 @SiO 2 @Tb-PDAN at pH 3, 5, 7, 8, 9 and 11, respectively, as shown in Fig.…”

Design of a novel green bio-based organic–inorganic hybrid material for cost-effective and sustainable monitoring of antibiotic residues

“…SPE column packing is essential for effective enrichment and purification. 26 To date, many traditional and novel SPE packing methods have been widely used to enrich target analytes, including C18, 27 hydrophilic-lipophilic balance (HLB), 28,29 carbon nanotubes (CNTs), 30 mesoporous silica nanoparticles, 31 molecularly imprinted polymers (MIPs), 32 covalent organic frameworks (COFs), 33,34 metalorganic frameworks (MOFs), 35 etc. Although these adsorbents have largely solved the problem of MAC enrichment and separation in complex matrices, most of them are consumable adsorbents, the raw materials involved are difficult to regenerate and degrade and there are still some problems including the complicated preparation process, which involves consumption of many organic reagents, harsh reaction conditions, single interaction, susceptibility to interference by co-existing components, and limited recovery.…”

Quantitative analysis of erythromycin, its major metabolite and clarithromycin in chicken tissues and eggs via QuEChERS extraction coupled with ultrahigh-performance liquid chromatography-tandem mass spectrometry

“…Compared with the LLE and SPE methods, QuEChERS is inexpensive, consumes low levels of reagents, saves time, and achieves relatively high recovery and precision ( Xu et al, 2021 ). The combination of QuEChERS and liquid chromatography tandem mass spectrometry has been widely used in MAC residual analysis ( Campanharo et al, 2023 , Du et al, 2021 , de Mendonça Pereira et al, 2021 , Xu et al, 2021 ). Du et al (2021) developed a QuEChERS method using multiwalled carbon nanotubes (MWCNTs) as the adsorbent, and 11 MACs in animal tissues and eggs were detected via ultrahigh-performance liquid chromatography tandem triple quadrupole mass spectrometry (UHPLC–MS/MS).…”

“…The combination of QuEChERS and liquid chromatography tandem mass spectrometry has been widely used in MAC residual analysis ( Campanharo et al, 2023 , Du et al, 2021 , de Mendonça Pereira et al, 2021 , Xu et al, 2021 ). Du et al (2021) developed a QuEChERS method using multiwalled carbon nanotubes (MWCNTs) as the adsorbent, and 11 MACs in animal tissues and eggs were detected via ultrahigh-performance liquid chromatography tandem triple quadrupole mass spectrometry (UHPLC–MS/MS). The average recoveries of 11 MACs in animal tissues and eggs were 83.5–111.4 %, and the corresponding intraday and interday relative standard deviations (RSDs) were less than 13.6 % and 16.4 %, respectively.…”