Determination of kresoxim-methyl and its thermolabile metabolites in pear utilizing pepper leaf matrix as a protectant using gas chromatography

Rahman, Md. Musfiqur; Jang, Jin; Park, Jong-Hyouk; El‐Aty, A. M. Abd; Ko, Ah-Young; Choi, Jeong‐Heui; Yang, Angel; Park, Ki Hun

doi:10.1016/j.jare.2013.05.003

Cited by 16 publications

(2 citation statements)

References 14 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Incorporating the pepper leaf matrix into the pear matrix ensured the integrity of the compounds, resulting in a precise and sensitive GC outcome for thermolabile kresoxim-methyl metabolites. The limits of detection (LOD) and quantification (LOQ) were determined to be 0.006 and 0.02 mg/kg for kresoxim-methyl and 0.02 and 0.065 mg/kg for the metabolites, respectively [ 39 ].…”

Section: Resultsmentioning

confidence: 99%

Development of an enhanced analytical method utilizing pepper matrix as an analyte protectant for sensitive GC‒MS/MS detection of dimethipin in animal-based food products

Shim,

Rahman,

Esatbeyoglu

et al. 2023

PLoS ONE

Self Cite

View full text Add to dashboard Cite

Herein, an analytical method using gas chromatography-tandem mass spectrometry (GC‒MS/MS) was devised to detect the presence of the troublesome pesticide dimethipin in various animal-based food products, including chicken, pork, beef, eggs, and milk. The injection port was primed with a matrix derived from pepper leaves that acts as an analyte protectant (AP) to safeguard the target compound from thermal degradation during gas chromatography. The presence of AP resulted in a remarkable limit of quantification of 0.005 mg/kg for dimethipin in five matrices. Three different versions (original, EN, and AOAC) of the QuEChERS (Quick, Easy, Cheap, Effective, Rugged, and Safe) method were compared for dimethipin extraction, with a double-layer solid-phase extraction (SPE) cartridge utilized for matrix purification. A seven-point external calibration curve was established for dimethipin in the five matrices, demonstrating excellent linearity with determination coefficients (R2) ≥ 0.998. The developed quantitative method was validated by fortifying each matrix with three different concentrations of standard dimethipin, and the average recovery fell within the acceptable range outlined in the CODEX guidelines (ranging from 88.8% to 110.0%), with a relative standard deviation (RSD) of ≤ 11.97%. This method effectively addresses the challenge of analyzing dimethipin and can therefore be used as a routine monitoring tool for dimethipin across various matrices.

show abstract

Section: Resultsmentioning

confidence: 99%

Development of an enhanced analytical method utilizing pepper matrix as an analyte protectant for sensitive GC‒MS/MS detection of dimethipin in animal-based food products

Shim,

Rahman,

Esatbeyoglu

et al. 2023

PLoS ONE

Self Cite

View full text Add to dashboard Cite

show abstract

“…The safety assessment indicates that tomato fruits may be regarded as safe for humans to eat. Deltamethrin was also reported to be safe in terms of application rate and pre-harvest interval in pear because the residue was 30 times lower than the MRL (1 mg kg −1 ) [25]. Blanching could be employed as a method of decontaminating Deltamethrin.…”

Section: Discussionmentioning

confidence: 99%

Residue dissipation kinetics, safety evaluation and decontamination of Deltamethrin in tomato and the soil

Majumder,

Singh,

Pandey

et al. 2024

Trends Hortic.

View full text Add to dashboard Cite

Tomato powdery mildew, fruit rot, and twig blight are all managed with Deltamethrin. Its residues could still be present in the crops, posing a health risk. The pesticide residue analysis, dissipation rate, and safety assessments were thus examined in green tomatoes. The analytical method for residue analysis was validated according to international standards. Tomato fruits and soil were used to study the dissipation of Deltamethrin 100 EC (11% w/w) at 12.5 g a.i ha−1 for the recommended dose (RD) and 25.0 g a.i ha−1 for the double of the recommended dose (DD). Ethyl acetate was used to extract residues from tomato fruit, and PSA and magnesium sulphate were used for cleanup.The fruits had recoveries ranging from 83% to 93% and the soil sample from 81.67% to 89.6%, with the limit of detection (LOQ) estimated at 0.01 mg kg−1. The matrix effect (ME) was calculated to be less than 20% for the tomato fruits and the soil.Half-lives for RD and DD were 1.95 and 1.84 days, respectively. All sampling days for both doses had dietary exposures of residues below the maximum permissible intake (MPI) of 0.16 mg person−1 day−1. The most effective method of decontaminating tomato residue containing Deltamethrin is blanching.

show abstract

Compensation for matrix effects in GC analysis of pesticides by using cucumber extract

et al. 2018

View full text Add to dashboard Cite

Matrix effects (MEs) can adversely affect quantification in pesticide residue analysis using GC. Analyte protectants (APs) can effectively interact with and mask active sites in the GC system, and are added individually or in combination to sample extracts and calibration solutions to minimize errors related to MEs. Unfortunately, APs cannot sufficiently compensate for MEs in all cases. Plant extracts, containing a broad range of natural compounds with AP properties, can also be used for this purpose. In this study, the applicability of cucumber extract as a natural AP mixture was investigated both alone and in combination with traditional APs. Extracts of two selected difficult matrices (onion and garlic) were prepared according to the citrate-buffered QuEChERS (quick, easy, cheap, effective, rugged, and safe) procedure. ME values of 40 representative GC-amenable pesticides were compared when calibrating against standards in pure solvent and in cucumber extract, with and without the addition of APs. Using a GC system with a contaminated inlet liner, the use of a cucumber-based calibration solution decreased MEs remarkably. The combination of APs with cucumber raw extract further decreased MEs, resulting in more than 85% of the tested pesticides showing ≤ 10% ME in onion and ≤ 20% ME in garlic. These results demonstrate that the preparation of calibration standards based on cucumber extracts (with or without the addition of APs) is a very useful and practical approach to compensate for MEs in pesticide residue analysis using QuEChERS and GC-MS/MS. The use of various internal standards is furthermore critically discussed.

show abstract

Determination of kresoxim-methyl and its thermolabile metabolites in pear utilizing pepper leaf matrix as a protectant using gas chromatography

Cited by 16 publications

References 14 publications

Development of an enhanced analytical method utilizing pepper matrix as an analyte protectant for sensitive GC‒MS/MS detection of dimethipin in animal-based food products

Development of an enhanced analytical method utilizing pepper matrix as an analyte protectant for sensitive GC‒MS/MS detection of dimethipin in animal-based food products

Residue dissipation kinetics, safety evaluation and decontamination of Deltamethrin in tomato and the soil

Compensation for matrix effects in GC analysis of pesticides by using cucumber extract

Contact Info

Product

Resources

About