Determination of Kojic Acid Based on a Poly(l-Arginine)-Electrochemically Reduced Graphene Oxide Modified Electrode

Abstract

A sensitive electroanalytical method for determination of kojic acid has been investigated on the basis of the enhanced electrochemical response at poly(L-arginine)-electrochemically reduced graphene oxide modified glassy carbon electrode fabricated by cyclic voltammetry. The glassy carbon electrode, poly(L-arginine) modified glassy carbon electrode, electrochemically reduced graphene oxide modified glassy carbon electrode, and poly(L-arginine)electrochemically reduced graphene oxide modified glassy carbon electrode were characterized by electrochemical impedance spectroscopy. The electrochemical behaviors of kojic acid were studied by cyclic voltammetry and differential pulse voltammetry in detail. Under optimal experiment conditions, the sensitive oxidation peak of kojic acid was appeared at 1.07 V and the calibration curves for kojic acid were obtained in the range of 7.50×10-7 − 1.00×10-4 mol L-1 and 1.00×10-9 − 5.00×10-7 mol L −1 with a detection limit of 1.0×10-9 mol L-1 (at an S/N of 3). This method has been applied to the determination of kojic acid in the rice wine samples with satisfactory results