Determination of intramedullary nail based on centerline adaptive registration

Abstract

Objective: Internal fixation with intramedullary nails is a gold standard for the treatment of femoral shaft fractures. However, both the mismatch between intramedullary nails and the medullary cavity and inaccurate positioning of entry points will lead to deformation of intramedullary nails after implantation. The study aimed to determine a suitable intramedullary nail with an optimal entry point for a specific patient based on centerline adaptive registration.Method: A homotopic thinning algorithm is employed to extract centerlines of the femoral medullary cavity and the intramedullary nail. The two centerlines are registered to obtain a transformation. The medullary cavity and the intramedullary nail are registered based on the transformation. Next, a plane projection method is employed to calculate the surface points of the intramedullary nail laid outside the medullary cavity. According to the distribution of compenetration points, an iterative adaptive registration strategy is designed to decide an optimal position of the intramedullary nail in medullary cavity. The isthmus centerline is extended to the femur surface, where the entry point of the intramedullary nail is located. The suitability of an intramedullary nail for a specific patient was calculated by measuring the geometric quantities reflecting the interference between the femur and nail, and the suitability values of all nails are compared and the most suitable one is determined.Results: The growth experiment indicated that the bone to nail alignment is indeed affected by the extension of the isthmus centerline, including the extension direction and velocity. The geometrical experiment showed that this method could find the best registration position of intramedullary nails and select the optimal intramedullary nail for a specific patient. In the model experiments, the determined intramedullary nail could be successfully placed into the medullary cavity through the optimal entry point. A pre-screening tool to determine nails which can be successfully used has been given. In addition, the distal hole was accurately located within 14.28 s.Conclusion: These results suggest that the proposed method can select a suitable intramedullary nail with an optimal entry point. The position of the intramedullary nail can be determined in the medullary cavity, while deformation is avoided. The proposed method can determine the largest diameter intramedullary nail with as little damage to the intramedullary tissue as possible. The proposed method provides preparation aid for internal fixation with intramedullary nails guided by navigation systems or extracorporeal aimers.