Determination of Initial Rates of Lipopolysaccharide Transport
Matthew Nava,
Sebastian J. Rowe,
Rebecca J. Taylor
et al.
Abstract:Nonvesicular lipid trafficking pathways are an important
process
in every domain of life. The mechanisms of these processes are poorly
understood in part due to the difficulty in kinetic characterization.
One important class of glycolipids, lipopolysaccharides (LPS), are
the primary lipidic component of the outer membrane of Gram-negative
bacteria. LPS are synthesized in the inner membrane and then trafficked
to the cell surface by the lipopolysaccharide transport proteins, LptB2FGCADE. By characterizing the i… Show more
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