Determination of Ibuprpfen in Aqueaus Solutions and Pharmacetical Preparations by UV-VIS Spectrophotometric

Abstract

A method has been developed for the determination of the ibuprofen drug in aqueous solution and pharmaceutical preparation using UV-Vis spectrophotometry. The opitimum experimental condition were based on the formation of complex compound and studied, the best temperature (303 k°), reaction time (13 min), solvent extraction (3 ml) and extraction time (5 min). Mole ratio and Job -method was used to found the ratio between the ligand (drug) and the metal ion (Co), the complex output ratio of (1:1). Detection of limit =0.223 µg/ml, Re% =96.8, r =0.9561, linearity (1x10 -3 -2x10 -2 M) and sandell sensitivity S =0.1008.

Ultraviolet light spectroscopic characterization of ibuprofen acid aggregation in deionized water

“…For this goal, we will make use of UV–Visible spectroscopy. This technique is typically employed to evaluate ibuprofen concentrations in solution (up to 500 ppm in buffered solutions [ [34] , [35] , [36] , [37] ], or in the 5–25 ppm range in pure water [ 38 ]). It is also known that the self-assembly of molecules with a low level of aggregation ( i.e.…”

Ultraviolet Light Spectroscopic Characterization of Ibuprofen Acid Aggregation in Deionized Water

“…For this goal, we will make use of UV-Visible spectroscopy. This technique is typically employed to evaluate ibuprofen concentrations in solution (up to 500 ppm in buffered solutions [34][35][36][37], or in the 5-25 ppm range in pure water [38]). It is also known that the self-assembly of molecules with a low level of aggregation (i.e., methylene blue) can be successfully studied by UV-Visible spectroscopy [39,40].…”

Comparative Study of Total Phenolics and Antioxidants in ASTRAGLUS STOCKSII by using Methanol, Ethanol and Acetone and to Evaluate its Anti -Inflammatory Activity

“…It is essential for the repair of damage tissues and for the conflict of pathogens. Nevertheless, it is also presuming in the creation and the maintenance of many disorders like asthma, rheumatoid arthritis, neurodegenerative disease, type 2 diabetes and chronic inflammatory bowel disease [12,13,28]. According to the report, plants are thought to inhibit inflammation by regulating the production of pro-inflammatory molecules.…”