Determination of hazardous volatile organic compounds in the Hoffmann list by ion‐molecule reaction mass spectrometry

Abstract

The IMR-MS technique can potentially result in reduced molecular fragmentation during analysis of VOCs. However, significant fragmentation still occurs during IMR-MS when the ionization energy (IE) of the ion reagent is much higher than the IE of the VOC, given that excess energy is stored in the newly formed ion during CT ionization. Given that IMR-MS cannot distinguish between isobaric compounds or isomers, we summarize the possible overlapping mass peaks from these isobaric species that may be present in analyses of VOCs. Selection of the ion reagent for IMR-MS should be based on the need to ensure CT ionization of the analytes, as well as avoiding their severe fragmentation.

Monitoring variations of dimethyl sulfide and dimethylsulfoniopropionate in seawater and the atmosphere based on sequential vapor generation and ion molecule reaction mass spectrometry

“…The IMRMS is a so-ionization mass spectrometer similar to PTRMS, but where chemical ionization is carried out using Hg + ions instead of H 3 O + (a mercury trap is installed so mercury vapor does not come out from the instrument.). 23,24 By coupling the mass spectrometer with sequential injection analysis-vapor generation (SIA-VG-IMRMS), dissolved DMS aq , DMS produced from DMSP, and atmospheric DMS g can be determined every 30 min. Sequential injection analysis is a useful method to automatically determine the trace compounds in marine water, 25,26 and coupling it with VG is very appropriate for volatile compounds, as we have previously demonstrated for the analysis of selenium in power plant wastewater.…”

Direct Analysis Mass Spectrometry

“…The applicability of the technology was further demonstrated when the IMR-MS technique was applied to the detection of volatiles present in cigarette smoke in which 20 VOCs were identified [43].…”

“…[219], using IMR-MS, applied the methodology to monitor volatiles in cigarette smoke but in order to do this it was necessary for them to establish the ion products of the reactions of the various reagent ions with analytes that might be present in cigarette smoke. This was achieved by making mixtures with known concentrations at the ppm level in nitrogen of individual hydrocarbons, aldehydes, nitriles, HCN, H 2 S, and chloromethane.…”

Increased sensitivity in proton-transfer-reaction time-of-flight mass spectrometry by using a novel traveling wave based ion-molecule reactor

“…7 In the past few decades, many efforts have been devoted to developing a new IMR. This device has many essential functions in the PTR-MS system, such as ionizing the sample molecules, 8 transmitting the ions, 7 and limiting the ion fragmentation. 8 The initial IMR uses a direct current electric field to transmit the product ions to the ion guide system through an orifice, 9 which causes severe ion loss.…”