Determination of Glyphosate in Dried Wheat by 1H-NMR Spectroscopy

Shumilina, Elena; Andreasen, Christian; Bitarafan, Zahra; Dikiy, Alexander

doi:10.3390/molecules25071546

Cited by 7 publications

(2 citation statements)

References 12 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The hydrocarbon group information of compounds can be identified by the chemical shift, coupling constant, splitting condition, integral area ratio and other information of hydrogen atoms. 1 H-NMR is the preferred NMR method in the analysis of organic compounds, especially trace compounds [2][3][4], because most compounds contain hydrogen atoms and 1 H-NMR has the characteristics of high sensitivity and can show large amount of information.…”

Section: Introductionmentioning

confidence: 99%

Analysis of the Alcohol Amine Mixtures by 1D Selective COSY

Zhang¹,

Guilan²,

Yang³

2022

View full text Add to dashboard Cite

Proton nuclear magnetic resonance ( 1 H-NMR) is one of the most commonly used techniques for structure identification in the field of chemical warfare convention (CWC) because of its strong ability in aiding structure assignment of chemicals. However, due to the lack of separation function coupled with chromatograph, the greatest disadvantage of 1 H-NMR in the analysis of environmental and biological samples is that the resonances can be easily covered or interfered. One-dimensional NMR selective excitation technology can effectively remove background interference and reveal the hidden spectral peak information. In this paper, three schedule chemicals of Chemical Weapons Convention (CWC), triethanolamine, N-methyldiethanolamine and 2-diisopropylaminoethanol, were selected as model chemicals. Homonuclear 1D COSY NMR selective excitation analysis method was established with these chemicals to solve the problem of resonances covered in 1 H-NMR. Key experiment parameters of 1D COSY were optimized. The optimized experimental conditions of 1D COSY are as follows: pulse sequence is selcogp, shaped pulse is G3, relaxation delay of d1 is 4 s, the excitation width of δ H 0.91 (a), 2.51 (g), 2.62 (e) and 3.44 (d) is 39.16, 35.34, 20.00 and 26.03 Hz respectively. The established 1D COSY method was used to analyze 1~10 µg/mL alcohol amine mixtures with 2 mg/mL quinuclidinol as the background interference and the LOD was 5 µg/mL. This method is simple, fast and can wipe off the interference effectively in the 1 H NMR spectrum without proceeding complex sample pretreatment. 1D selective COSY reflects the more accurate position of hydrogen atom, and can be used as a reliable auxiliary technology for structural identification.

show abstract

Section: Introductionmentioning

confidence: 99%

Analysis of the Alcohol Amine Mixtures by 1D Selective COSY

Zhang¹,

Guilan²,

Yang³

2022

View full text Add to dashboard Cite

show abstract

“…Weeds compete with crop plants for various resources, such as nutrients, water, and sunlight, which significantly affect crop productivity. Besides, weeds also increase crop protection costs because they harbor pests and bacterial diseases [1][2][3]. Herbicide application has been a prominent weed-control measure in recent decades under field conditions [4,5].…”

Section: Introductionmentioning

confidence: 99%

New Lead Discovery of Herbicide Safener for Metolachlor Based on a Scaffold-Hopping Strategy

et al. 2020

View full text Add to dashboard Cite

The use of herbicide safeners can significantly alleviate herbicide injury to protect crop plants and expand the application scope of the existing herbicides in the field. Sanshools, which are well known as spices, are N-alkyl substituted compounds extracted from the Zanthoxylum species and have several essential physiological and pharmacological functions. Sanshools display excellent safener activity for the herbicide metolachlor in rice seedlings. However, the high cost of sanshools extraction and difficulties in the synthesis of their complicated chemical structures limit their utilization in agricultural fields. Thus, the present study designed and synthesized various N-alkyl amide derivatives via the scaffold-hopping strategy to solve the challenge of complicated structures and find novel potential safeners for the herbicide metolachlor. In total, 33 N-alkyl amide derivatives (2a–k, 3a–k, and 4a–k) were synthesized using amines and saturated and unsaturated fatty acids as starting materials through acylation and condensation. The identity of all the target compounds was well confirmed by 1H-NMR, 13C-NMR, and high-resolution mass spectrometry (HRMS). The primary evaluation of safener activities for the compounds by the agar method indicated that most of the target compounds could protect rice seedlings from injury caused by metolachlor. Notably, compounds 2k and 4k displayed excellent herbicide safener activities on plant height and demonstrated relatively similar activities to the commercialized compound dichlormid. Moreover, we showed that compounds 2k and 4k had higher glutathione S-transferase (GST), superoxide dismutase (SOD), catalase (CAT), peroxidase (POD), and polyphenol oxidase (PPO) activities in rice seedlings, compared to the metolachlor treatment. In particular, 2k and 4k are safer for aquatic organisms than dichlormid. Results from the current work exhibit that compounds 2k and 4k have excellent crop safener activities toward rice and can, thus, be promising candidates for further structural optimization in rice protection.

show abstract

BSA-carbon dots a promising “off–on” fluorescence probe for detecting glyphosate residues in agricultural products

Wang,

Zheng

et al. 2023

Carbon Lett.

View full text Add to dashboard Cite

Determination of Glyphosate in Dried Wheat by 1H-NMR Spectroscopy

Cited by 7 publications

References 12 publications

Analysis of the Alcohol Amine Mixtures by 1D Selective COSY

Analysis of the Alcohol Amine Mixtures by 1D Selective COSY

New Lead Discovery of Herbicide Safener for Metolachlor Based on a Scaffold-Hopping Strategy

BSA-carbon dots a promising “off–on” fluorescence probe for detecting glyphosate residues in agricultural products

Contact Info

Product

Resources

About