Determination of Glucose-Dependent Dielectric Properties of Ringer Lactate Using Open-Ended Coaxial Probe Method

Singh, Satish; Sen, Kushal; Anand, Sneh

doi:10.1007/s12647-016-0179-z

Cited by 7 publications

(2 citation statements)

References 21 publications

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“…In this context, a series of in-vitro experiments are performed on different types of aqueous-based solutions having different Dextrose-glucose (D-glucose) concentrations using different types of measuring systems over a wide range of frequencies varying from audio to microwave spectrum. The first experiment based on the open-ended coaxial method was conducted to observe the effect of D-glucose concentration on the dielectric properties of ringer lactate (RL) solution from 100 MHz to 2.5 GHz as reported in previous published work [19,20]. The RL was chosen in the experiment as its chemical composition is similar to interstitial fluids [21].…”

Section: Correlation Between Dielectric Properties and Glucose Concen...mentioning

confidence: 99%

Analysis of glucose‐dependent dielectric properties of aqueous‐based solution: A proof of concept

Singh

Sen²,

Anand

2021

IET Science Measure & Tech

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In spite of widespread research and exploration, the status of non-invasive blood glucometer for diabetic people is far from satisfactory. This unlocks the prospect for further significant research in the field of non-invasive blood glucose sensing. An approach towards the research on the development of non-invasive blood glucometer relies on the establishment of correlation, if any, exists between the dielectric properties of blood and the blood glucose level. In this context, the in-vitro study is undertaken as a proof of concept using a standard liquid-dielectric-test-fixture. The research is conducted to analyse the variation in dielectric properties of aqueous-based solution with respect to glucose concentration by utilising test fixture. The employed measurement set-up and the procedure used for the estimation of dielectric properties (complex-relative-permittivity and dissipation factor) of the solution under test are presented. The measurement set-up is validated by determining the dielectric properties of the reference liquid. The evaluation of uncertaintyin-measurement in the complex-relative-permittivity and dissipation factor is also provided in detail. However, the variation in dielectric properties is found to be small under tested conditions, and the in-vitro study conducted out in the perspective of proof of concept has provided an insight that the change in glucose concentration results in quantifiable variation in dielectric properties.This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

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Section: Correlation Between Dielectric Properties and Glucose Concen...mentioning

confidence: 99%

Analysis of glucose‐dependent dielectric properties of aqueous‐based solution: A proof of concept

Singh

Sen²,

Anand

2021

IET Science Measure & Tech

Self Cite

View full text Add to dashboard Cite

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“…Invasive methods are, therefore, the more popular means of blood glucose monitoring at microwave frequencies. Various invasive sensing schemes using rectangular 18 , 19 and cylindrical cavity sensors 20 , dielectric resonator 21 , band stop filter 22 , distributed microelectromechanical systems (MEMS) transmission line (DMTL) 23 , coaxial probes 24 , 25 , etc. are in use.…”

Section: Introductionmentioning

confidence: 99%

Design of an ELC resonator-based reusable RF microfluidic sensor for blood glucose estimation

Govind

Akhtar

2020

Sci Rep

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Design of a reusable microfluidic sensor for blood glucose estimation at microwave frequencies is presented. The sensing unit primarily comprises a complementary electric LC (CELC) resonator, which is made reusable by filling the test sample in a glass capillary before mounting it inside a groove cut in the central arm of the resonator. The use of glass capillary in the present situation to contain the blood sample actually eliminates the possibility of any direct contact of the sensor with the test sample, and hence wards off any coincidental contamination of the sensor. Usage of the capillary provides additional benefits as only microliters of the sample are required, besides offering sterile measuring environment since these capillaries are disposable. The capillary made of borosilicate glass is highly biocompatible and exhibits exceptionally high chemical resistance in corrosive environments. Apart from reusability, the novelty of the proposed sensor also lies in its enhanced sensitivity which is quite an essential factor when it comes to the measurement of glucose concentration in the human physiological range. The applicability of the proposed scheme for glucose sensing is demonstrated by performing RF measurements of aqueous glucose solutions and goat blood samples using the fabricated sensor.

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Demonstration of Microstrip Sensor for the Feasibility Study of Non-invasive Blood-Glucose Sensing

Singh

Sen

Anand

2020

MAPAN

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Determination of Glucose-Dependent Dielectric Properties of Ringer Lactate Using Open-Ended Coaxial Probe Method

Cited by 7 publications

References 21 publications

Analysis of glucose‐dependent dielectric properties of aqueous‐based solution: A proof of concept

Analysis of glucose‐dependent dielectric properties of aqueous‐based solution: A proof of concept

Design of an ELC resonator-based reusable RF microfluidic sensor for blood glucose estimation

Demonstration of Microstrip Sensor for the Feasibility Study of Non-invasive Blood-Glucose Sensing

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