Background and Purpose-Despite the importance of exercise training in mitigating cardiovascular risk, the development of exercise programs for people poststroke has been limited by lack of feasibility data concerning cardiopulmonary exercise testing (CPET) to inform the exercise prescription. Therefore, we examined the feasibility of CPETs for developing an exercise prescription in people Ն3 months poststroke. Methods-CPET results from 98 consecutively enrolled patients poststroke with motor impairments and 98 age-and sex-matched patients with coronary artery disease were examined at baseline and after 6 months of exercise training. Results-The proportion of patients with stroke and coronary artery disease attaining an intensity sufficient for prescribing exercise at baseline was 68.4% versus 82.7%, respectively (Pϭ0.02) and 84.7% versus 83.8% (Pϭ0.9) at 6 months. Women were less likely than men poststroke to achieve a sufficient intensity at baseline (40% versus 80.9%, PϽ0.001) but not at 6 months (78.3% versus 87.1, Pϭ0.3). A clinically relevant abnormality occurred in 11.2% of stroke and 12.2% of patients with coronary artery disease on baseline CPETs (Pϭ0.8) and 10.6% of stroke and 5.9% of patients with coronary artery disease on the 6-month CPET (Pϭ0.4). No serious cardiovascular events occurred during 349 CPETs. Key Words: electrocardiography Ⅲ rehabilitation Ⅲ stroke care Ⅲ stroke delivery Ⅲ stroke recovery D espite exercise being an important component of stroke rehabilitation, there is a dearth of information on the clinical use and feasibility of cardiopulmonary exercise testing (CPET) for individuals with a history of stroke before engaging in exercise. This issue merits special attention in view of the growing recognition of the importance of exercise in the secondary prevention of stroke and the risk of comorbid coronary artery disease (CAD).
Conclusions-MostCPETs are not routinely administered before starting a cardiac rehabilitation (CR) program after stroke. 1 Consequently, exercise is often prescribed without an objective assessment of the patients' functional capacity, resting and exercise blood pressures, exercise-related symptoms, and/or electrocardiographic (ECG) changes including dysrhythmias. 2 Despite recommendations to base exercise prescriptions on CPET results, few data are available to substantiate the feasibility and safety of graded exercise tests with ECG monitoring after stroke. 3 Lacking this information has hindered the development of exercise programs tailored to the functional capacities of survivors of stroke.A CPET involves measuring oxygen uptake, carbon dioxide output, and minute ventilation at the same time as monitoring blood pressure and 12-lead ECG. Measures derived from the CPET guide the activity attributes of the exercise prescription. From both a safety and efficacy point of view, the most important parameter of the prescription is that of intensity. 4 -6 Intensity of exercise is believed to be the primary factor responsible for change in peak oxygen uptake (VO 2p...