Determination of estrogenic mycotoxins in environmental water samples by low-toxicity dispersive liquid–liquid microextraction and liquid chromatography–tandem mass spectrometry

Emídio, Elissandro Soares; Silva, Claudia Pereira da; Marchi, Mary Rosa Rodrigues de

doi:10.1016/j.chroma.2015.02.067

Cited by 29 publications

(10 citation statements)

References 39 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The selection of an appropriate extraction solvent is of great importance in an LDS‐DLLME process. To obtain efficient extraction, the extraction solvent has to fulfill some requirements such as low density compared to water, low solubility in water, reproducibility, and good GC behavior . Many reports regarding DLLME have used chlorinated solvents such as dichloromethane, chloroform, carbon tetrachloride, tetrachloroethylene, chlorobenzene, etc.…”

Section: Resultsmentioning

confidence: 99%

Simultaneous dispersive liquid–liquid microextraction based on a low‐density solvent and derivatization followed by gas chromatography for the simultaneous determination of chloroanisoles and the precursor 2,4,6‐trichlorophenol in water samples

Zhang

Yang

2016

J of Separation Science

View full text Add to dashboard Cite

Chloroanisoles, particularly 2,4,6-trichloroanisole, are commonly identified as major taste and odor compounds in water. In the present study, a simple and efficient method was established for the simultaneous determination of chloroanisoles and the precursor 2,4,6-trichlorophenol in water by using low-density-solvent-based simultaneous dispersive liquid-liquid microextraction and derivatization followed by gas chromatography with electron capture detection. 2,4-Dichloroanisole, 2,6-dichloroanisole, 2,4,6-trichloroanisole, 2,3,4-trichloroanisole, and 2,3,6-trichloroanisole were the chloroanisoles evaluated. Several important parameters of the extraction-derivatization procedures, including the types and volumes of extraction solvent and disperser solvent, concentrations of derivatization agent and base, salt addition, extraction-derivatization time, and temperature were optimized. Under the optimized conditions (80 μL of isooctane as extraction solvent, 500 μL of methanol as disperser solvent, 60 μL of acetic anhydride as derivatization agent, 0.75% of Na2 CO3 addition w/v, extraction-derivatization temperature of 25°C, without salt addition), a good linearity of the calibration curve was observed by the square of correlation coefficients (R(2) ) ranging from 0.9936 to 0.9992. Repeatability and reproducibility of the method were < 4.5% and <7.3%, respectively. Recovery rates ranged from 85.2 to 101.4%, and limits of detection ranged from 3.0 to 8.7 ng/L. The proposed method was applied successfully for the determination of chloroanisoles and 2,4,6-trichlorophenol in water samples.

show abstract

Section: Resultsmentioning

confidence: 99%

Simultaneous dispersive liquid–liquid microextraction based on a low‐density solvent and derivatization followed by gas chromatography for the simultaneous determination of chloroanisoles and the precursor 2,4,6‐trichlorophenol in water samples

Zhang

Yang

2016

J of Separation Science

View full text Add to dashboard Cite

show abstract

“…The results revealed that extraction efficiencies of these solvents were comparable and higher than using the chlorinated solvents. Good sensitivity with relatively lower limit of detection was also obtained [22][23][24][25][26]. Compared to chlorinated solvents, some of the brominated and iodinated solvents have lower toxicity [22,26,27].…”

Section: Introductionmentioning

confidence: 83%

Untitled

2018

MJAS

View full text Add to dashboard Cite

Dispersive liquid-liquid microextraction (DLLME) is a novel sample preparation technique that has higher level of extraction efficiency by means of relying on microvolumes of solvents. It has gained considerable attention from researchers owing to several advantages such as its simplicity, shorter extraction time, lower cost and higher enrichment factor. In conventional DLLME, chlorinated solvents are widely used as the extraction solvents. Notwithstanding, most of these solvents are reportedly toxic and environmentally-unfriendly. Many related studies in recent years have focused on the use of nontoxic or low toxic extraction solvents and better practical procedures, which have helped improve the extraction efficiency. The aim of this review is to discuss the development of low toxic extraction solvent used recently in the DLLME. The possible improvement of extraction solvent from the green analytical chemistry perspectives is also discussed.Keywords: extraction solvents, dispersive liquid-liquid microextraction, green analytical chemistry Abstrak Pengekstrakan mikro cecair-cecair serakan (DLLME) merupakan teknik penyediaan sampel novel yang mempunyai lebih tinggi kecekapan pengekstrakan dengan menggunakan mikroliter pelarut. Teknik ini telah mendapat perhatian daripada penyelidik kerana beberapa kelebihan seperti ringkas, masa pengekstrakan yang lebih pendek, kos yang lebih rendah dan faktor pengayaan yang lebih tinggi. Dalam DLLME konvensional, pelarut berklorin digunakan secara meluas sebagai pelarut pengekstrakan. Namun, kebanyakan pelarut ini dilaporkan toksik dan tidak mesra alam. Dalam tahun kebelakangan ini, banyak kajian yang berkaitan telah fokus kepada penggunaan pelarut pengekstrakan yang tidak bertoksik atau rendah toksik dan praktikal prosedur yang lebih baik telah meningkatkan kecekapan pengekstrakan. Tujuan kajian ini adalah untuk membincangkan perkembangan pelarut pengekstrakan rendah toksik yang digunakan dalam DLLME terkini. Penambahbaikan pelarut pengekstrakan dari perspektif kimia analisis hijau juga dibincangkan.Kata kunci: pelarut pengekstrakan, pengekstrakan mikro cecair-cecair serakan, kimia analitik hijau

show abstract

“…Since it was introduced by Rezaee et al . in 2006, various modifications of primary DLLME in recent decades have been reported, including ionic liquid‐based DLLME, low‐density solvent‐based DLLME, DLLME based on solidification of floating organic droplets, surfactant‐assisted DLLME, shaker‐assisted DLLME, vortex‐assisted DLLME, microwave‐assisted DLLME, ultrasound‐assisted DLLME, dual DLLME, and novel automated DLLME . The in situ derivatization is gaining more interest as sample preparation technique .…”

mentioning

confidence: 99%

“…Dispersive liquid-liquid microextraction (DLLME) is a rapid, economical and environmentally benign samplepretreatment technique being widely used in the analysis of EDCs in environmental matrices, food samples, and biological samples. [35][36][37] Since it was introduced by Rezaee et al in 2006, [38] various modifications of primary DLLME in recent decades have been reported, including ionic liquid-based DLLME, [39] low-density solvent-based DLLME, [40] DLLME based on solidification of floating organic droplets, surfactant-assisted DLLME, shaker-assisted DLLME, [41] vortex-assisted DLLME, microwave-assisted DLLME, ultrasound-assisted DLLME, [42,43] dual DLLME, [44,45] and novel automated DLLME. [45] The in situ derivatization is gaining more interest as sample preparation technique.…”

mentioning

confidence: 99%

Rapid and sensitive determination of multiple endocrine‐disrupting chemicals by ultrasound‐assisted in situ derivatization dispersive liquid–liquid microextraction coupled with ultra‐high‐performance liquid chromatography/tandem mass spectrometry

Wei

Zheng

Wang

et al. 2017

Rapid Comm Mass Spectrometry

View full text Add to dashboard Cite

show abstract

Determination of estrogenic mycotoxins in environmental water samples by low-toxicity dispersive liquid–liquid microextraction and liquid chromatography–tandem mass spectrometry

Cited by 29 publications

References 39 publications

Simultaneous dispersive liquid–liquid microextraction based on a low‐density solvent and derivatization followed by gas chromatography for the simultaneous determination of chloroanisoles and the precursor 2,4,6‐trichlorophenol in water samples

Simultaneous dispersive liquid–liquid microextraction based on a low‐density solvent and derivatization followed by gas chromatography for the simultaneous determination of chloroanisoles and the precursor 2,4,6‐trichlorophenol in water samples

Untitled

Rapid and sensitive determination of multiple endocrine‐disrupting chemicals by ultrasound‐assisted in situ derivatization dispersive liquid–liquid microextraction coupled with ultra‐high‐performance liquid chromatography/tandem mass spectrometry

Contact Info

Product

Resources

About