Determination of dimethylnitrosamine and nitrosoproline by differential pulse polarography

Liquid chromatographic determination of nitrosamines in malt and beer with a photoconductivity detector

“…The occurrence of carcinogenic nitrosamines (NAs) in the environment and in a variety of food products has spurred interest in their detection and quantitation. Earlier attempts to separate and detect NAs in foods have included colorimetry (1,2), TLC (1, 3), GLC (4-7), HPLC (8)(9)(10), polarography (11)(12)(13)(14), and GLC derivative formation (15)(16)(17)(18). All of these techniques suffered from serious drawbacks including, lack of sensitivity, selectivity, reliable instrumentation and/or detectors, or inadequate separation from sample matrices.…”

Electrochemical Reduction of Prilocaine as itsN-Nitrosamine Derivative at the Mercury Electrode

“…The polarographic behavior of some N-nitrosamines has been investigated [12][13][14][15][16][17] and pulse polarography has been found to be a very sensitive technique for N-nitrosamine determinations. Although its rather poor selectivity makes impossible the specific determination of one type of N-nitrosamine in the presence of another one without a prior separation step, polarography, however, has a number of advantages: it can be applied to both volatile and nonvolatile compounds, it provides a rapid analysis with simple and inexpensive apparatus and it does not require sample preparation.…”

Determination of nitrosamines by a photo-electrochemical method

“…and NO^ (83). Although the technique had a detection limit in the ppb region, no application of this technique was reported.…”

“…This is the Polarography has been used for the determination of nitrosamines (80)(81)(82), but the method suffers from inter ferences by pyrazines which are very common in foods (56,60). Differential pulse polarography has been investigated for the determination of nitrosamines (83,84) but suffers from interferences caused by reduction of O2…”