Determination of dimethyl sulfoxide and dimethyl sulfone in air

Lang, Russell F.; Brown, Cheryl J.

doi:10.1021/ac00002a019

Cited by 13 publications

(6 citation statements)

References 40 publications

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“…Apart from microbial enzymatic reactions and endogenous metabolism of methionine, DMSO 2 can directly enter the physiological DMSO 2 pool from external sources, which can contribute to the overall host metabolic phenotype. Organic sulfur compounds, including DMS, DMSO, and DMSO 2 , are part of a global sulfur cycle in the marine ocean–atmosphere system. , DMSO and DMSO 2 are water-soluble, existing naturally in the earth’s surface water, seawater, rainwater, and air; however, the presence of DMSO 2 is not as abundant as DMSO. − DMS, DMSO, and DMSO 2 also accumulate in edible green algae, Capsosiphon fulvescens, constituting a dietary source in seaweed-consuming individuals …”

Section: Dimethyl Sulfone (Dmso2) From External Sourcesmentioning

confidence: 99%

Metabolic Fingerprint of Dimethyl Sulfone (DMSO₂) in Microbial–Mammalian Co-metabolism

Slupsky

2014

J. Proteome Res.

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There is growing awareness that intestinal microbiota alters the energy harvesting capacity of the host and regulates metabolism. It has been postulated that intestinal microbiota are able to degrade unabsorbed dietary components and transform xenobiotic compounds. The resulting microbial metabolites derived from the gastrointestinal tract can potentially enter the circulation system, which, in turn, affects host metabolism. Yet, the metabolic capacity of intestinal microbiota and its interaction with mammalian metabolism remains largely unexplored. Here, we review a metabolic pathway that integrates the microbial catabolism of methionine with mammalian metabolism of methanethiol (MT), dimethyl sulfide (DMS), and dimethyl sulfoxide (DMSO), which together provide evidence that supports the microbial origin of dimethyl sulfone (DMSO2) in the human metabolome. Understanding the pathway of DMSO2 co-metabolism expends our knowledge of microbial-derived metabolites and motivates future metabolomics-based studies on ascertaining the metabolic consequences of intestinal microbiota on human health, including detoxification processes and sulfur xenobiotic metabolism.

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Section: Dimethyl Sulfone (Dmso2) From External Sourcesmentioning

confidence: 99%

Metabolic Fingerprint of Dimethyl Sulfone (DMSO₂) in Microbial–Mammalian Co-metabolism

Slupsky

2014

J. Proteome Res.

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“…2,7,12,13 In recent years methods reported in the literature have used solid adsorbent preconcentration followed by thermal desorption and gas chromatography for the analysis of volatile organic compounds in air. Examples include trace levels of formaldehyde, 14 lower-molecular-weight hydrocarbons, 15,16 the chemicalwarfare agent mustard gas, 17 volatile hydrocarbons in indoor air, 18 dimethyl sulfoxide and dimethyl sulfone in air, 19 or polycyclic aromatic hydrocarbons. 20 Recently, a multistage solid adsorbent trapping system has also been developed for analysis of ppt-level volatile organic trace gases (especially halocarbons).…”

Section: Introductionmentioning

confidence: 99%

Field sampling of trace levels of hydrogen sulfide with the use of solid adsorbent preconcentration

Dévai

DeLaune

1997

Field Analyt. Chem. Technol.

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“…However, the significance of the role of DMSO in the DMS cycling has still to be assessed. This task is hampered by the scarcity of reliable analytical methods for DMSO determination in the environment.Owing to the difficulties in the measurement of nanomolar DMSO levels in water matrices with direct chromatographic methods, 11,24,25 reduction and subsequent gas-phase analysis of the DMS produced appears to be the technique of choice. Sodium borohydride 26 and titanium trichloride 6 have been used as reducing agents.…”

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confidence: 99%

Sequential Method for the Field Determination of Nanomolar Concentrations of Dimethyl Sulfoxide in Natural Waters

1996

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A procedure for the determination of dimethyl sulfoxide (DMSO), along with dimethyl sulfide (DMS) and dimethyl sulfoniopropionate (DMSP), at nanomolar levels in natural waters has been developed. After removal of DMS by purge and cryotrapping, DMSP is removed by the same method after alkaline hydrolysis, and DMSO is reduced to DMS using a combination of sodium borohydride and hydrochloric acid. The DMS produced is stripped, cryotrapped, and analyzed by gas chromatography. Detection of 3 pmol of DMSO was achieved, resulting in a detection limit of 0.05 nM for a 50 mL sample. Mean yield for standards in the range 0.7-130 nM (n = 31) was 95%, and mean precision (as coefficient of variation) was 14%. Precision for replicates of natural seawater samples was always ≤10%. Mean yields of the sequential analysis of DMS + DMSP + DMSO (1.5-25 nM) standard mixtures in seawater were >90% for the three species. Filtered seawater samples stored frozen (-20 °C) showed no significant changes in DMSO concentration. Since DMSP is the only compound, other than DMSO, that gives rise to DMS upon reduction with NaBH(4), tests were performed to ensure that DMSP is quantitatively removed before the DMSO analysis. Boranes were identified as the substances that produced two major peaks in the chromatogram of the reduction products. Adequate chromatographic conditions were established to avoid their coelution with DMS. This entire protocol allows the sequential determination of DMS, DMSP, and DMSO in natural waters and is suitable for field work, so it should be very useful in studies of dimethyl sulfur biogeochemistry. Some examples of DMSO (along with DMS and DMSP) measurements in the Mediterranean Sea are presented.

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Determination of dimethyl sulfoxide and dimethyl sulfone in air

Cited by 13 publications

References 40 publications

Metabolic Fingerprint of Dimethyl Sulfone (DMSO₂) in Microbial–Mammalian Co-metabolism

Metabolic Fingerprint of Dimethyl Sulfone (DMSO₂) in Microbial–Mammalian Co-metabolism

Field sampling of trace levels of hydrogen sulfide with the use of solid adsorbent preconcentration

Sequential Method for the Field Determination of Nanomolar Concentrations of Dimethyl Sulfoxide in Natural Waters

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Determination of dimethyl sulfoxide and dimethyl sulfone in air

Cited by 13 publications

References 40 publications

Metabolic Fingerprint of Dimethyl Sulfone (DMSO2) in Microbial–Mammalian Co-metabolism

Metabolic Fingerprint of Dimethyl Sulfone (DMSO2) in Microbial–Mammalian Co-metabolism

Field sampling of trace levels of hydrogen sulfide with the use of solid adsorbent preconcentration

Sequential Method for the Field Determination of Nanomolar Concentrations of Dimethyl Sulfoxide in Natural Waters

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Product

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Metabolic Fingerprint of Dimethyl Sulfone (DMSO₂) in Microbial–Mammalian Co-metabolism

Metabolic Fingerprint of Dimethyl Sulfone (DMSO₂) in Microbial–Mammalian Co-metabolism