Cadmium concentrations were assessed in the hepatic tissues of 27 Guiana dolphins, Sotalia guianensis, that were found stranded in the estuary of Cananéia-Iguape, southeast of Brazil, between 2009 and 2012. The samples' digestion was performed through acid digestion with HNO 3 and the quantification was held by flame atomic absorption spectrometry (FAAS). For 11 of the sampled animals, concentrations did not exceed the limit of quantification of 0.1µg.g -1 stipulated by the method. The concentrations varied from above detection limit to 1.79µg.g -1 (wet weight), for a average of 0.39µg.g -1 which is in accord with the literature, as low values of the metal were commonly found in the tissues of the specie on the Brazilian coast. No differences were observed in the accumulation of cadmium between sexes, age classes or the curvilinear length. The accumulation found in the livers may reflect the Guiana dolphins diet in the region and the bioavailability of the metal in the system. This study provides new data about the accumulation of cadmium in animals of the Brazilian coast, contributing towards the status of conservation of the specie.