Determination of bisphenol a migration from food packaging by dispersive liquid-liquid microextraction

Abstract

In the current work, a rapid and simple dispersive liquid-liquid microextraction method (DLLME) was used to determine Bisphenol A (BPA). High performance liquid chromatography with the photodiode-array detector (HPLC-DAD) coupled DLLME method was employed to analyze BPA in food samples packaged including cans, paper boxes, and glass jars. The calibration curve was obtained to be in the linear range 0.009–25 ngg −1 with a correlation coefficient of R2 = 0.9981. The mean relative standard deviations (RSDs) was of 5.2% ( n = 3). The limit of detection (LOD) and the limit of quantification (LOQ) of the method were obtained to be 0.001 ngg −1 and 0.08 ng.g −1 , respectively. In sum, this method presents: A rapid, simple and efficient modified DLLME method was used to measure BPA in packaged foods. The advantages of this method were low detection limit, fast preparation, and high BPA recovery. The DLLME-HPLC method consists of low detection limit and high recoveries to determine BPA in samples. The results indicated that DLLME –HPLC-DAD was an applied method to measure BPA in food samples.

Bisphenol A analysis and quantification inconsistencies via HPLC-UV: a systematic review with technical notes

“…B Overlapped main purposes with other secondary objectives of the analyzed papers [64] or by air pollution near polycarbonate molding plants [65], bee pollen [66], mussels [67] and brine shrimp [68]. Food contamination was determined in meat samples [53], beverages [55,69,70], milk [59,63,71,72], oils [56,63], and canned food products [59,71,73] with most studies revealing that BPA could be leached from the plastic can linings, packaging, and bottles [53,55,56,71,[74][75][76].…”

“…However, the wavelengths used varied around the specific peaks of BPA: 34.55% of the analyzed studies quantified BPA in a spectrum range between λ max = 200 and λ max = 220 nm, 25.45% between λ max = 224 and λ max = 230 nm, and a significant number of papers representing 32.73% of the entire literature survey determined BPA at wavelengths between λ max = 270 and λ max = 280 nm. Interestingly, 3 groups of authors [41,71,73] chose to set the detection of BPA by HPLC-UV at the wavelength of λ max = 254 nm. Selection of this wavelength value is very popular in HPLC analysis although in most cases the absorption maxima is not even close.…”

Enhanced adsorption/extraction of bisphenols by pyrrolic N-based 3D magnetic carbon nanocomposites for effervescence-assisted solid-phase microextraction of bisphenols from juices and the underlying interaction mechanisms

“…To date, several analytical approaches have been reported for BP quantification, such as solid-phase microextraction(SPME) [10], dispersive liquid-liquid microextraction (DLLME) [9,11], and effervescent tablet-assisted dispersive solid-phase microextraction (ET-DSM) [8,12,13]. The ET-DSM method incorporating an effervescent reaction, as pioneered by Lasarte-Aragones and coworkers, is often a preferred method owing to its convenient operation and remote/outdoor feasibility [13].…”

Editorial overview: Virtual collection on chromatographic and mass spectrometric methods in food, health, and agriculture

“…The methodology of Mahdavianpour et al. [6] outlines a simple dispersive liquid-liquid microextraction (DLLME) pre-treatment which was coupled with HPLC-DAD to determine the content of BPA in a sampling of commercial foods packaged in cans, paper boxes, and glass jars. This procedure provides a rapid, cost-effective concentration protocol for high-throughput sampling, while providing a low limit of detection and high BPA recovery.…”