Determination of beta‐agonists in swine hair by μFIA and chemiluminescence

Abstract

β-Agonists are a group of illegal feed additives. In this paper, it was found that the light emission produced by the oxidation of luminol by potassium ferricyanide was enhanced by the β-agonists (ractopamine, salbutamol, and terbutaline). Based on chemiluminescence phenomenon, a novel, rapid, and sensitive microflow injection analysis system on a microfluidic glass chip was established for determination of the β-agonists. The chip was fabricated from two glass plates (64 mm × 32 mm) with microchannels of 200 μm width and 100 μm depth. The detection limits were achieved at 2.0 × 10(-8) mol/L of ractopamine, 1.0 × 10(-8) mol/L of terbutaline and 5.0 × 10(-7) mol/L of salbutamol. In this report, our method was applied for determination of the β-agonists in swine hair from three different sources with satisfactory results.

Investigation on a Sensitive Chemiluminescence System Based on Ni(IV) Complex to Determine Two β2-Agonist Drugs in Urine and Swine Feed and Their Mechanism

“…Unlike other methods, chemiluminescence (CL), due to its more sensitive, economical, convenient and lower detection limits, has attracted considerable attention in several fields such as clinical research, biotechnology, pharmacology, and environmental chemistry [14][15][16][17] in the recent years. Several chemiluminescence systems has been successfully used in determination for SAL and TEB in different oxidants, such as K3[Fe(CN)6] [18,19], H2O2 [20], and Cu(III) complex [21], others are such as Immunoassay CL [22], Micro Flow Sensor [23] and Liquid-Core Waveguide CL detection system [24]. N(CH 3 …”

Luminol Chemiluminescence Catalyzed by Silver Nanoparticles for the Sensitive Determination of Penicillamine

“…The major advantages of CL have led to the extensive utilization of this technique for detection of analytes using flow injection analysis, sequential injection analysis, microfluidics, capillary electrophoresis and high performance liquid chromatography [28][29][30][31][32][33][34][35]. The major attraction to CL detection in these techniques stems from the high sensitivity and the simple instrumentation as only a photomultiplier tube is required, eliminating the use of expensive optics required by other techniques such as fluorescence spectroscopy.…”