Determination of Anti-Mycoplasma Capricolum Subsp. Capripneumoniae Antibodies For The Sero-Epidemiology of Contagious Caprine Pleuropneumonia

Abstract

Contagious caprine pleuro-pneumonia (CCPP) is fatal disease of goats and causes huge economic losses due to high morbidity and mortality. CCPP is enlisted as notifiable animal disease by OIE. The causative agent of CCPP is Mycoplasma capricolum subsp. capripneumoniae (Mccp). The present study was aimed to investigate the seroprevalence of CCPP in northern Pakistan. The study areas were divided into three zones; northern zone, central zone and tribal zone. A total of 1300 serum samples were collected during November 2017 – April 2019 from goats of different age and sex and were analysed by monoclonal antibody based cELISA. The analyses revealed 227 (17.5%) samples positive for anti-Mccp antibodies. The zone wise distribution of CCPP in goats was significantly different (P˂0.05), indicated by positive sera for Mccp of 23% animals from northern zone followed by 15% and 13% animals from tribal and central zones, respectively. The analysis of data showed non-significant values in the seroprevalence among bucks and doe(s), indicated by anti-Mccp sera from 16.6% bucks and 18.3% doe (s). Moreover, among different age groups the prevalence of disease in adult goats (20%) was significantly (P˂0.05) higher than kids (10.8%). It is evident from the present study that CCPP caused by Mccp is prevalent in Pakistan and both sex of animals are equally susceptible to Mccp infection. Furthermore the disease is more prevalent in northern zone.