“…First, we could only trace a small portion of the degradation products that may be formed from the administered TGOOH. Based on the reports by Kanazawa et al [ 8 , 48 ] and other investigators that proposed the degradation pathway of lipid hydroperoxides [ 37 , 49 , 50 ], it appears that TGOOH is degraded in the gastrointestinal tract to yield breakdown products such as aldehydes. Since such compounds appear to be transported into the systemic circulation [ 48 , 51 , 52 ], future studies should broaden the scope of analysis to include other biological samples ( e.g., blood and liver).…”