Determination of 5-nitroimidazole residues in milk by capillary electrochromatography with packed C18 silica beds

Hernández‐Mesa, Maykel; Lara, Francisco J.; Cruces‐Blanco, Carmen; Garcı́a-Campaña, Ana M.

doi:10.1016/j.talanta.2015.06.049

Cited by 17 publications

(3 citation statements)

References 47 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…A proper set-up of buffer composition and concentration, capillary length, and voltage allowed a reproducible analysis of eight 5-NDZs in milk samples in 15 min. In addition, a sample pretreatment using LLE and SPE methods highly increased the method sensitivity (LOQ range for all the 5-NDZs analyzed was 19-96 µg/L) [38]. This method, combining the advantages of CE and HPLC, was more selective and rapid than the simple HPLC [39] or CZE [40] methods.…”

Section: Nitroimidazolesmentioning

confidence: 99%

Advances in the Analysis of Veterinary Drug Residues in Food Matrices by Capillary Electrophoresis Techniques

Colombo

Papetti

2019

Molecules

View full text Add to dashboard Cite

In the last years, the European Commission has adopted restrictive directives on food quality and safety in order to protect animal and human health. Veterinary drugs represent an important risk and the need to have sensitive and fast analytical techniques to detect and quantify them has become mandatory. Over the years, the availability of different modes, interfaces, and formats has improved the versatility, sensitivity, and speed of capillary electrophoresis (CE) techniques. Thus, CE represents a powerful tool for the analysis of a large variety of food matrices and food-related molecules with important applications in food quality and safety. This review focuses the attention of CE applications over the last decade on the detection of different classes of drugs (used as additives in animal food or present as contaminants in food products) with a potential risk for animal and human health. In addition, considering that the different sample preparation procedures have strongly contributed to CE sensitivity and versatility, the most advanced sample pre-concentration techniques are discussed here.

show abstract

Section: Nitroimidazolesmentioning

confidence: 99%

Advances in the Analysis of Veterinary Drug Residues in Food Matrices by Capillary Electrophoresis Techniques

Colombo

Papetti

2019

Molecules

View full text Add to dashboard Cite

show abstract

“…Hernández‐Mesa et al. prepared capillary column packed with a mixture of Bidentate C18 for separation of eight antibiotics belonging to 5‐nitroimidazole family by means of CEC coupled with MS. LOD values were between 0.09 and 0.42 μg/mL for all compounds.…”

Section: Column Techniquementioning

confidence: 99%

Recent advances in microscale separation

et al. 2017

View full text Add to dashboard Cite

Recent advances in microscale separationThis review focuses on the recent advances on microscale separation technology, particularly on the new development on column and detection technologies in electrophoretic and chromatographic separation modes (i.e., CE, CEC, cLC, etc.). Representative examples illustrate also applications on the small molecules, peptides, proteins, polysaccharides, chiral and so on. 246 relevant articles are cited covering the literature published

show abstract

“…These columns offer higher surface area which improves sample loading capacity and are commercially available but have certain disadvantages such as bubble formation, column fragility and high price. A novel methodology by CEC‐UV was developed for the analysis of nine 5‐nitroimidazole (dimetridazole, ronidazole, carnidazole, ornidazole, metrodinazole, tinidazole, ipronidazole, secnidazole, ternidazole) residues in milk samples using lab‐made packed columns (produced by a high pressure procedure that employed acetone as driving solvent, C 18 silica particles (5 μm) as packing material and capillary frits of nichrome ribbon (80% Ni‐20% Cr)) . Under the optimized experimental conditions, eight out of nine antibiotics analyzed (all except tinidazole that co‐eluted with secnidazole) were separated in less than 15 min with good sensitivity and precision.…”

Section: Ce and Cec With Uv Detectionmentioning

confidence: 99%

Analysis of antibiotics by CE and CEC and their use as chiral selectors: An update

et al. 2017

View full text Add to dashboard Cite

Natural, synthetic or semisynthetic antibiotics are highly used to prevent or treat diseases in humans and animals, and to promote animal growth. This fact makes that antibiotics residues or their transformation products may be present in food or in the environment after human or animal excretion. For this reason, it is imperative to develop reliable and sensitive analytical methodologies for their analysis. The main aim of this work is to present and discuss the most recent applications of capillary electromigration methods for the analysis of antibiotics, including the developments and applications of their use as chiral selectors in CE. The literature published from June 2015 to June 2017 is included following the previous review by Domínguez‐Vega et al. (Electrophoresis, 2016, 37, 189–211). Information about the use of different detection systems, off‐line and on‐line strategies to improve sensitivity, and microchip devices for the analysis of antibiotics is provided and properly discussed.

show abstract

Determination of 5-nitroimidazole residues in milk by capillary electrochromatography with packed C18 silica beds

Cited by 17 publications

References 47 publications

Advances in the Analysis of Veterinary Drug Residues in Food Matrices by Capillary Electrophoresis Techniques

Advances in the Analysis of Veterinary Drug Residues in Food Matrices by Capillary Electrophoresis Techniques

Recent advances in microscale separation

Analysis of antibiotics by CE and CEC and their use as chiral selectors: An update

Contact Info

Product

Resources

About