Determinants of the interval between diagnosis and treatment in patients with digestive tract cancer

Mariscal, María Luisa Martín; Llorca, José Pérez; Prieto-Salceda, Dolores; Palma, S; Delgado-Rodrı́guez, Miguel

doi:10.3892/or.10.2.463

Cited by 9 publications

(19 citation statements)

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“…Those who recognised the symptom or who had previous experience of a symptom or of cancer itself tended to delay less (MacDonald and Freeling, 1986;Samet et al, 1988;Dent et al, 1990;Porta et al, 1996;Sladden et al, 1999). This was also the case for those with comorbidity (Ratcliffe et al, 1989;Mor et al, 1990;Porta et al, 1996;Mariscal et al, 2001) and those experiencing multiple symptoms (Mariscal et al, 2001).…”

Section: Presenting Symptom and Patient Historymentioning

confidence: 99%

“…Furthermore, there was no relationship between delay and lower socioeconomic status (Hackett et al, 1973;Worden and Weisman, 1975;MacAdam, 1979;MacArthur and Smith, 1984;Samet et al, 1988;Prohaska et al, 1990;Porta et al, 1996;Langenbach et al, 2003), although some studies suggested that this might be associated with increased delay. Rural residence (Robinson et al, 1986;Bain et al, 2002) and lower levels of education (Marshall and Funch, 1986;Dent et al, 1990;Vineis et al, 1993;Porta et al, 1996;Mariscal et al, 2001;Cockburn et al, 2003;McCaffery et al, 2003) were both found to increase delay.…”

Section: Patient Characteristicsmentioning

confidence: 99%

“…Only five studies used primary care records (9%). Median patient delay ranged from 7 days to 5 months (Worden and Weisman, 1975;Turunen and Peltokallio, 1982;MacArthur and Smith, 1984;Funch, 1985;Robinson et al, 1986;Ratcliffe et al, 1989;Dent et al, 1990;Curless et al, 1994;Arbman et al, 1996;Porta et al, 1996;Mulcahy and O'Donoghue, 1997;Majumdar et al, 1999;Mariscal et al, 2001) and practitioner delay from 0 to 15 months (Turunen and Peltokallio, 1982;MacArthur and Smith, 1984;Funch, 1985;Ratcliffe et al, 1989;Mansson, 1990;Jones and Dudgeon, 1992;Curless et al, 1994;Arbman et al, 1996;Harris and Simson, 1998;Majumdar et al, 1999;Mariscal et al, 2001). …”

Section: Delay Intervalsmentioning

confidence: 99%

“…For the most part, patients who suffered from more serious symptoms such as obstruction or abdominal pain delayed less (Devlin et al, 1973;MacAdam, 1979;Rubin et al, 1980;MacArthur and Smith, 1984;Prohaska et al, 1990;Mulcahy and O'Donoghue, 1997;Majumdar et al, 1999;Young et al, 2000;Mariscal et al, 2001), whereas those experiencing either nonspecific symptoms or more common symptoms, such as bleeding or altered bowel habit, delayed longer (Devlin et al, 1973;Galloway et al, 1984;Mor et al, 1990;Curless et al, 1994). There were, however, some patients for whom pain resulted in increased delay (Hackett et al, 1973;Nilsson et al, 1982;MacArthur and Smith, 1984;Prohaska et al, 1990).…”

Section: Presenting Symptom and Patient Historymentioning

confidence: 99%

“…By and large, patient age (Worden and Weisman, 1975;MacAdam, 1979;McDermott et al, 1981;Turunen and Peltokallio, 1982;Pitluk and Poticha, 1983;Galloway et al, 1984;MacArthur and Smith, 1984;Marshall and Funch, 1986;Robinson et al, 1986;Samet et al, 1988;Dent et al, 1990;Mor et al, 1990;Prohaska et al, 1990;Marble et al, 1992;Kemppainen et al, 1993;Curless et al, 1994;Arbman et al, 1996;Porta et al, 1996;Mulcahy and O'Donoghue, 1997 Factor included only if supported by studies providing strong or moderate levels of evidence * Found in .50% of studies considering factor; * * found in .75% of studies considering factor 1999; Mariscal et al, 2001;McCaffery et al, 2003) and sex (Worden and Weisman, 1975;MacAdam, 1979;McDermott et al, 1981;Turunen and Peltokallio, 1982;Marshall and Funch, 1986;Robinson et al, 1986;Samet et al, 1988;Dent et al, 1990;Kemppainen et al, 1993;Porta et al, 1996;Mulcahy and O'Donoghue, 1997;Majumdar et al, 1999;Sladden et al, 1999;Young et al, 2000;Mariscal et al, 2001;Cockburn et al, 2003;McCaffery et al, 2003) had no impact on delay. Furthermore, there was no relationship between delay and lower socioeconomic status …”

Section: Patient Characteristicsmentioning

confidence: 99%

See 4 more Smart Citations

Influences on pre-hospital delay in the diagnosis of colorectal cancer: a systematic review

et al. 2007

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Colorectal cancer is a major global health problem, with survival varying according to stage at diagnosis. Delayed diagnosis can result from patient, practitioner or hospital delay. This paper reports the results of a review of the factors influencing pre-hospital delay -the time between a patient first noticing a cancer symptom and presenting to primary care or between first presentation and referral to secondary care. A systematic methodology was applied, including extensive searches of the literature published from 1970 to 2003, systematic data extraction, quality assessment and narrative data synthesis. Fifty-four studies were included. Patients' non-recognition of symptom seriousness increased delay, as did symptom denial. Patient delay was greater for rectal than colon cancers and the presence of more serious symptoms, such as pain, reduced delay. There appears to be no relationship between delay and patients' age, sex or socioeconomic status. Initial misdiagnosis, inadequate examination and inaccurate investigations increased practitioner delay. Use of referral guidelines may reduce delay, although evidence is currently limited. No intervention studies were identified. If delayed diagnosis is to be reduced, there must be increased recognition of the significance of symptoms among patients, and development and evaluation of interventions that are designed to ensure appropriate diagnosis and examination by practitioners.

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Section: Presenting Symptom and Patient Historymentioning

confidence: 99%

Section: Patient Characteristicsmentioning

confidence: 99%

Section: Delay Intervalsmentioning

confidence: 99%

Section: Presenting Symptom and Patient Historymentioning

confidence: 99%

Section: Patient Characteristicsmentioning

confidence: 99%

See 3 more Smart Citations

Influences on pre-hospital delay in the diagnosis of colorectal cancer: a systematic review

et al. 2007

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Investigación sobre las desigualdades en la incidencia, mortalidad, prevención y atención del cáncer en España

et al. 2011

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Systematic review of factors influencing patient and practitioner delay in diagnosis of upper gastrointestinal cancer

et al. 2006

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As knowledge on the causation of cancers advances and new treatments are developed, early recognition and accurate diagnosis becomes increasingly important. This review focused on identifying factors influencing patient and primary care practitioner delay for upper gastrointestinal cancer. A systematic methodology was applied, including extensive searches of the literature published from 1970 to 2003, systematic data extraction, quality assessment and narrative data synthesis. Included studies were those evaluating factors associated with the time interval between a patient first noticing a cancer symptom and presenting to primary care, between a patient first presenting to primary care and being referred to secondary care, or describing an intervention designed to reduce those intervals. Twenty-five studies were included in the review. Studies reporting delay intervals demonstrated that the patient phase of delay was greater than the practitioner phase, whilst patient-related research suggests that recognition of symptom seriousness is more important than recognition of the presence of the symptom. The main factors related to practitioner delay were misdiagnosis, application and interpretation of tests, and the confounding effect of existing disease. Greater understanding of patient factors is required, along with evaluation of interventions to ensure appropriate diagnosis, examination and investigation.

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Determinants of the interval between diagnosis and treatment in patients with digestive tract cancer

Cited by 9 publications

References 0 publications

Influences on pre-hospital delay in the diagnosis of colorectal cancer: a systematic review

Influences on pre-hospital delay in the diagnosis of colorectal cancer: a systematic review

Investigación sobre las desigualdades en la incidencia, mortalidad, prevención y atención del cáncer en España

Systematic review of factors influencing patient and practitioner delay in diagnosis of upper gastrointestinal cancer

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