1997
DOI: 10.1002/(sici)1098-1101(1997)12:2<74::aid-jca4>3.0.co;2-6
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Determinants of the efficacy of prophylactic granulocyte transfusions: A meta-analysis

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Cited by 72 publications
(23 citation statements)
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“…9 We looked at neither the prevalence of alloimmunization nor the compatibility between the patients and the granulocyte units for transfusion. A potential confounding factor is the time effect.…”
Section: Discussionmentioning
confidence: 99%
“…9 We looked at neither the prevalence of alloimmunization nor the compatibility between the patients and the granulocyte units for transfusion. A potential confounding factor is the time effect.…”
Section: Discussionmentioning
confidence: 99%
“…There is renewed interest in the use of granulocytes for transfusion therapy, with recognition that the most effective treatments are associated with higher doses of cells 2,5,17 . Therefore, it is vital that the most stimulative and effective reagents be used for the apheresis collection procedure.…”
Section: Discussionmentioning
confidence: 99%
“…The use of granulocyte transfusions is increasing and is finding particular application in the treatment of life‐threatening bacterial and fungal infections in immunosuppressed patients 1–3 . It is known that the effectiveness of the preparation is related to the number of cells in the component transfused 4,5 .…”
mentioning
confidence: 99%
“…The results of the trials and the subsequent availability of growth factors probably contributed to the decline of this practice [63]. A 1997 meta-analysis concluded that prophylactic GTX could “no longer be recommended”, arguing that the the effect on prevention of infections detected by the first studies would be negligible in the presence of more effective antibiotics and colony growth factors [64]. …”
Section: Gtx For Prophylaxis Of Infectionmentioning
confidence: 99%