Determinants of Quality of Life in Patients with Post-Thrombotic Syndrome

Silva, Joana Cruz; Constâncio, Vânia; Lima, Pedro; Nunes, Celso; Silva, Eduardo; Anacleto, Gabriel; Fonseca, Manuel

doi:10.1016/j.avsg.2022.03.002

Cited by 6 publications

(4 citation statements)

References 36 publications

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“…Early mobilization also applies to patients after endovascular recanalization techniques [17] and superficial thrombophlebitis. Interestingly, patients with PTS who have a good adherence to their compression stockings showed similar scores in QoL as patients without PTS, underlining the importance of this intervention [44]. Below-knee stockings are better tolerated than above-knee stockings.…”

Section: Compression Therapymentioning

confidence: 87%

Physiotherapy in Chronic Venous Disease

Eidenberger

2023

Physical Therapy - Towards Evidence-Based Practice

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Chronic venous disease is a highly prevalent disorder. Risk factors are obesity, smoking, orthostasis, and family history. Pathophysiology encompasses changes such as venous hypertension, reflux, valve incompetencies, and calf-muscle weakness. Patients complain about skin changes, leg edema, pain, and ulcers. Possible recurrence of varicoses and surgery complications shift the focus on conservative approaches. The mainstay is compression therapy, applied by using multi-layer compression bandages or adequate compression stockings. Active exercises tackle muscle pump weakness, ankle joint restrictions, and physical activity. Aerobic exercises focus on lower limb activities (walking, cycling, aqua exercises) and are complemented by resistance exercises and muscle stretching. The gait pattern needs analysis and adaptation. Breathing exercises and manual lymphatic drainage act as a supplement. A critical factor for success is the patient’s adherence to lifestyle changes and health behavior. Therapists must motivate, guide, and educate their patients. They advise them on clothes/shoes and activities of daily life.

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Section: Compression Therapymentioning

confidence: 87%

Physiotherapy in Chronic Venous Disease

Eidenberger

2023

Physical Therapy - Towards Evidence-Based Practice

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“…With development, skin ulcers become aggravated or even systemic infections can occur (8). Furthermore, chronic post-thrombotic syndrome on the left lower extremity was characterized by extremity pain, edema, venous claudication, skin changes and skin ulceration, and inflammatory responses impaired the skin barrier functions (9)(10)(11)(12). As regards the patient in the present study, the swollen and fragile skin and soft tissue of the limbs, followed by frequent exposure to and stimulation by the shrimp pond water environment for a long period of time, may have led to further damage to the skin barrier.…”

Section: Discussionmentioning

confidence: 99%

Skin and soft tissue infection suspiciously caused by Klebsiella pneumoniae in an aquaculture worker: A case report

Xie,

Li,

Chen

et al. 2024

Med Int

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Skin and soft tissue infections (SSTIs), which are mainly caused by Gram-positive cocci existing on the skin surface, are more common than those caused by Gram-negative bacteria; however, the role of Gram-negative bacteria as emerging pathogens in SSTIs cannot to be ignored. Klebsiella pneumoniae is an opportunistic pathogenic bacterium that mainly inhabits the respiratory and intestinal tracts of humans and animals, as well as the environment, including aquaculture farms. This bacterium can cause multiple infections in humans and animals. The present study reports the case of a SSTI which was suspected to be caused by Klebsiella pneumoniae in a 74-year-old farmer with venous thrombosis. The patient had exposed his four bare limbs to the farmed shrimps and shrimp pond routinely. Pustule and skin ulcers were observed on both the legs of the patient. After receiving anti-infection therapy, the SSTI was almost completely resolved on day 9 and the patient was then discharged.

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“…Patients with PTS who were compliant to compression stockings had similar QoL scores to patients without PTS in a previous study. 18 Additionally, physical activity might be promoted by the use of smart watches and similar devices, which are useful for both monitoring and supporting healthy lifestyle interventions. 19 The poorest QoL was found in patients with a permanent stent occlusion.…”

Section: Discussionmentioning

confidence: 99%

Quality of Life after Venous Stenting for Post-thrombotic Syndrome and the Effect of Inflow Disease

Bakas,

van Montfrans,

Moelker

et al. 2023

Vasc Endovascular Surg

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Objective Patients with PTS experience an impaired quality of life (QoL). We aimed to study QoL in patients stented for post thrombotic syndrome (PTS) and analyze the influence of different parameters. Methods Patients stented for PTS after iliofemoral deep vein thrombosis were asked to complete the Chronic Venous Disease Quality of Life Questionnaire (CIVIQ-20) and the Short Form Health Survey (SF-36) in this cross-sectional study. All other data were collected retrospectively. Primary endpoints were median CIVIQ-20 and physical (PCS) and mental (MCS) component summary SF-36 scores. The influence of age, sex, and years between the procedure and completion of questionnaire were investigated using a multivariate linear regression model. Wilcoxon signed rank test compared the PCS and MCS with the normative. Effects of inflow from the deep femoral vein (DFV) and/or the femoral vein (FV) on QoL was analyzed in patients with patent stents. Results The response rate was 70.3% (n = 45/64). Time period (median) from stenting to questionnaire completion was 6.6 years (IQR: 8.0). Most stents were placed unilateral left-sided (73.3%). For patients with patent stents (n = 42) median CIVIQ-20 was 35.5 (IQR: 17.3), higher than the minimum of 20.0 ( P < .001). Median PCS of 44.7 (IQR: 14.2) was lower ( P < .001), and MCS of 55.9 (IQR: 7.1) higher ( P = .001) than the normative (50.0). Time since stenting and sex were not associated with QoL. Age was a significant predictor [standardized coefficient ß = .36, P = .04] for QoL using the CIVIQ-20, but not for the SF-36. Inflow disease did not impact QoL, but patients with occluded stents (n = 3) had poor functioning levels. Conclusion Quality of life is impaired after venous stenting for PTS, particularly physical functioning, among patients with an open stent, but was similar between patients with good and impaired inflow. Patients with a permanent stent occlusion had the lowest QoL.

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Determinants of Quality of Life in Patients with Post-Thrombotic Syndrome

Cited by 6 publications

References 36 publications

Physiotherapy in Chronic Venous Disease

Physiotherapy in Chronic Venous Disease

Skin and soft tissue infection suspiciously caused by Klebsiella pneumoniae in an aquaculture worker: A case report

Quality of Life after Venous Stenting for Post-thrombotic Syndrome and the Effect of Inflow Disease

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