Determinants of postoperative acute kidney injury

Abstract

Introduction Development of acute kidney injury (AKI) during the perioperative period is associated with increases in morbidity and mortality. Our aim was to evaluate the incidence and determinants of postoperative AKI after major noncardiac surgery in patients with previously normal renal function.

Two acute kidney injury risk scores for critically ill cancer patients undergoing non-cardiac surgery

“…[1][2][3][4] But there were no validation studies of these risk scores, which restrict the use of these indexes. Thus, the assessment of these AKI risk scores is important before its use in clinical practice.…”

“…Two AKI risk scores were calculated according to Kheterpal's [1] and Abelha's [3] definition. In Kheterpal's AKI risk score, five classifications were based on nine preoperative risk factors (Table 1).…”

“…Several risk scores have been developed in predicting AKI for patients undergoing general surgery [1,3] or specifi c operations such as cardiac surgery. [5] These data are of interest to surgeons who attempt to decrease the risk of AKI after surgery.…”

“…The aim of the present study is to evaluate the use of two acute kidney injury risk soreses for patients who underwent non-cardiac surgery and required intensive care. [1,3] …”

Perioperative Organ Protection in Cardiac Surgery

“…The sensibility of kidneys to ischemic insults can culminate in acute kidney injury (AKI), more common in large surgeries and where extensive bleeding is present, especially if associated with hemodynamic instability, and is an independent risk factor for hospital mortality (92). Although acute renal failure requiring renal replacement therapy after cardiac surgery is rare, it has a devastating impact on outcome (93).…”