Determinants of perioperative morbidity and mortality after pneumonectomy

Wahi, Rakesh; McMurtrey, Marion J.; DeCaro, Louis F.; Mountain, Clifton F.; Ali, Mohsin; Smith, Terry L.; Roth, Jack A.

doi:10.1016/0003-4975(89)90172-0

Cited by 207 publications

(86 citation statements)

References 19 publications

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“…A história clíni-ca, o diagnóstico e o tipo de cirurgia são mais importantes para identificar pacientes de risco 40 . A taxa de mortalidade per-operatória após pneumectomia em idosos é alta, e mesmo obtendo precisa avaliação pré-operatória do VEF 1.0 e VEF 1.0 /CV, não é possível identificar aquele paciente que apresenta risco elevado 41 . Pacientes portadores de Doença Pulmonar Obstrutiva Crônica grave, com VEF 1.0 abaixo de 2 litros, geralmente estão associados a alto risco de complicações pulmonares pós-operatória.…”

Section: Mortalidade E Morbidade Pulmonar Pós-operatóriaunclassified

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O sistema respiratório e o idoso: implicações anestésicas

Fernandes¹,

Neto²

2002

Rev. Bras. Anestesiol.

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RESUMO Fernandes CR, Ruiz Neto PP -O Sistema Respiratório e o Idoso: Implicações Anestésicas Justificativa e Objetivos -As complicações respiratórias são responsáveis por grande parte dos óbitos após procedimentos c i r ú r g i c o s q u e o c o r r e m n a p o p u l a ç ã o g e r i á t r i c Conteúdo -São apresentadas as alterações respiratórias fisiológicas do envelhecimento. São enfatizadas as alterações de volume e capacidades pulmonares, da mecânica respiratória e de trocas gasosas proporcionadas pela a n e s t e s i a . S ã o a b o r d a d o s a s p e c t o s r e l a t i v o s à morbimortalidade pulmonar pós-operatória em geriatria

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Section: Mortalidade E Morbidade Pulmonar Pós-operatóriaunclassified

“…Clinical history, diagnosis and type of surgery are more important to identify risk patients 40 . Post-pneumectomy mortality rate in elderly is high and, even with a precise preoperative VEF 1.0 and VEF 1.0 /VC evaluation, it is not possible to identify patients at increased risk 41 .…”

Section: Preoperative Pulmonary Function Evaluationmentioning

confidence: 99%

O sistema respiratório e o idoso: implicações anestésicas

Fernandes¹,

Neto²

2002

Rev. Bras. Anestesiol.

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“…The association of postoperative AF with mortality is documented after lung surgery, major noncardiac surgery, and nonthoracic operations [6,12,14,[28][29][30]. Postoperative AF after open esophagectomy is reported to cause a high incidence of postoperative complications, high hospital mortality rate, and increased costs due to prolonged hospital stay.…”

Section: Discussionmentioning

confidence: 99%

Predictive factors for postoperative tachyarrhythmia after thoracoscopic esophagectomy and the usefulness of landiolol hydrochloride for its treatment

et al. 2013

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Background Tachyarrhythmia after esophagectomy is a severe complication that should not be underestimated because of its negative impact. The aims of this study were to clarify the cause and impact of postoperative tachyarrhythmia after thoracoscopic esophagectomy. Additionally, we analyzed the usefulness of landiolol administration for postoperative tachyarrhythmia. Methods We evaluated the predictive factors for tachyarrhythmia onset after surgery and its clinical impact in 127 patients who underwent thoracoscopic esophagectomy with extended lymphadenectomy. Moreover, we analyzed the efficacy of landiolol for postoperative tachyarrhythmia. Results Tachyarrhythmia developed in 38 of the 127 patients. Multivariate analysis showed that advanced age, heart disease, and hyperlipidemia were associated with postoperative tachyarrhythmia. Hyponatremia, hypoalbuminemia, and leukocytosis on postoperative day 3 were significantly associated with tachyarrhythmia onset. The incidence of all complications and respiratory complications, including pneumonia, was significantly higher in patients with than in those without tachyarrhythmia. The mortality rate in the tachyarrhythmia group tended to be higher than that in the nontachyarrhythmia group. Landiolol as a treatment for tachyarrhythmia immediately decreased heart rate and safely reduced subsequent respiratory complications. ConclusionIn elderly patients with cardiac disease or hyperlipidemia, surgeons should be alert for the occurrence of tachyarrhythmia after esophagectomy. Postoperative tachyarrhythmia is a marker of morbidities with particular emphasis on respiratory complications. However, it can be adequately managed by landiolol, resulting in fewer respiratory complications. Landiolol might be a safe and convenient agent for managing postoperative tachyarrhythmia after thoracoscopic esophagectomy, resulting in lower mortality and morbidity rates.

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“…These authors were the first to use percentage of predicted values instead of absolute values. Subsequently, others have confirmed that perioperative risk increase substantially when the ppoFEV 1 is <40% of predicted normal (17)(18)(19)(20)(21)(22)(23).…”

Section: Pulmonary Function Evaluationmentioning

confidence: 96%

Preoperative functional workup for patients with advanced lung cancer

Brunelli

2016

J. Thorac. Dis.

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Locally advanced lung cancer remains a surgical indication in selected patients. This condition often demands larger resections. As a consequence preoperative functional workup is of paramount importance to stratify the risk and choose the most appropriate treatment. We reviewed the current evidence on functional evaluation with a special focus on specific aspects related to locally advanced lung cancer stages (i.e., risk after neoadjuvant treatment, pneumonectomy). Evidence is discussed to provide information that could assist clinicians in their preoperative workup of these challenging patients.

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Determinants of perioperative morbidity and mortality after pneumonectomy

Cited by 207 publications

References 19 publications

O sistema respiratório e o idoso: implicações anestésicas

O sistema respiratório e o idoso: implicações anestésicas

Predictive factors for postoperative tachyarrhythmia after thoracoscopic esophagectomy and the usefulness of landiolol hydrochloride for its treatment

Preoperative functional workup for patients with advanced lung cancer

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