Determinants of mortality after hypothermic circulatory arrest in a chronic porcine model

Juvonen, Tatu; Biancari, Fausto; Rimpiläinen, Jussi; Anttila, Vesa; Pokela, Matti; Vainionpää, Vilho; Romsi, Pekka; Kiviluoma, Kai

doi:10.1016/s1010-7940(01)00955-1

Cited by 6 publications

(2 citation statements)

References 15 publications

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“…It is detected that bleeding increases within the ones who had partial cardiopulmonary bypass [6]. In the critical patients, if cardiac functions and the oxygen amount reaching the heart can be provided within the optimal conditions during and after the operation, mortality and morbidity decrease noticeably [7,8]. In our case, the patient has requiring coronary bypass surgery.…”

Section: Discussionmentioning

confidence: 63%

What Should Be Done if There Is Coronary Artery Disorder in Ruptured Abdominal Aortic Aneurysm?

Simsek¹,

Bayraktaroğlu²,

Bayram³

et al. 2011

WJCS

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Abdominal aortic aneurysm (AAA) is the most common type of aneurismal diseases. Generally, it is asymptomatic and when it is ruptured, it develops with high morbidity and mortality. Case report: A 62-years-old male patient consulted our emergency with a pain at his dorsum and lumbar part. Cardiologist with a suspicion of coronary artery disorder or dissection, coronary angiography was executed. Consecutive lesions of LAD artery (left anterior descending) 40% -50% and 90%, CX artery (circumflex) 40% and 80% -90%, and a lesion of RCA (right coronary artery) 20% -30% were detected. With a suspicion of rupture, abdominal aneurysm tomography (CT) was demanded. In the tomography, a 7-cm-diameter ruptured abdominal aortic aneurysm was diagnosed. Levosimendan support was started. Under the support of levosimendan a Y graft operation was performed. The operation was ended up with levosimendan support considering that coronary bypass would increase mortality and morbidity. Discussion: Approximately 50% of the ruptured aneurysms are died before they reach hospital while the 30% -70% operated ones are died within 30 days after operation. Early diagnosis and follow-up is extremely important to decrease morbidity and mortality. The patients consulting with rupture must be taken to the operation without delay. What should be done if coronary artery disorder is detected in the patient whose AAA is ruptured and if the bypass is necessary? In our opinion, a decision must be made according to the patient's clinical condition. As a result of our case, we thought repairing the abdominal aortic aneurysm necessitates the other comorbidites must be treated medically. We aimed to decrease the cardiac oxygen requirement by starting levosimendan and decline afterload. If the patient, whose coronary artery disorder is detected, is under risk and his overall condition is bad, we think that coronary bypass operation can be delayed.

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Section: Discussionmentioning

confidence: 63%

What Should Be Done if There Is Coronary Artery Disorder in Ruptured Abdominal Aortic Aneurysm?

Simsek¹,

Bayraktaroğlu²,

Bayram³

et al. 2011

WJCS

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“…Apart from the results of each single study performed, it was our interest to evaluate thoroughly our experience in order to better understand the pathogenesis of brain ischemic injury and to identify the determinants of outcome after experimental HCA, thus, the targets for potential effective treatments (2,3).…”

mentioning

confidence: 99%

Increase of Intracranial Pressure after Hypothermic Circulatory Arrest in a Chronic Porcine Model

Pokela

Romsi

Biancari

et al. 2002

Scandinavian Cardiovascular Journal

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pH-Stat Versus α-Stat Acid–Base Management Strategy During Hypothermic Circulatory Arrest Combined With Embolic Brain Injury

Dahlbacka

Heikkinen

Kaakinen

et al. 2005

The Annals of Thoracic Surgery

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Determinants of mortality after hypothermic circulatory arrest in a chronic porcine model

Abstract: Parameters of oxyhemodynamics should be monitored especially from the induction of anesthesia to the end of cooling before a 75-min period of HCA. The use of medetomidine and/or 35% of oxygen at induction of anesthesia should be avoided in favor of ketamine plus 100% of oxygen.

Cited by 6 publications

References 15 publications

What Should Be Done if There Is Coronary Artery Disorder in Ruptured Abdominal Aortic Aneurysm?

What Should Be Done if There Is Coronary Artery Disorder in Ruptured Abdominal Aortic Aneurysm?

Increase of Intracranial Pressure after Hypothermic Circulatory Arrest in a Chronic Porcine Model

pH-Stat Versus α-Stat Acid–Base Management Strategy During Hypothermic Circulatory Arrest Combined With Embolic Brain Injury

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