2009
DOI: 10.1152/ajpheart.01334.2008
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Determinants of left ventricular shear strain

Abstract: matical models of cardiac mechanics can potentially be used to relate abnormal cardiac deformation, as measured noninvasively by ultrasound strain rate imaging or magnetic resonance tagging (MRT), to the underlying pathology. However, with current models, the correct prediction of wall shear strain has proven to be difficult, even for the normal healthy heart. Discrepancies between simulated and measured strains have been attributed to 1) inadequate modeling of passive tissue behavior, 2) neglecting active str… Show more

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Cited by 56 publications
(65 citation statements)
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References 45 publications
(84 reference statements)
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“…1). With respect to geometry, material properties, and the circulation in which the LV is embedded, this FE model is identical to the model presented in extenso in Bovendeerd et al (6). Characteristics important for this article are repeated here for readability.…”
Section: Model Of Left Ventricular Mechanicsmentioning
confidence: 99%
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“…1). With respect to geometry, material properties, and the circulation in which the LV is embedded, this FE model is identical to the model presented in extenso in Bovendeerd et al (6). Characteristics important for this article are repeated here for readability.…”
Section: Model Of Left Ventricular Mechanicsmentioning
confidence: 99%
“…Experimentally it has been shown that a considerable component of active stress may be generated perpendicular to the myofiber direction (19). Extension from uniaxial to triaxial active stress development in models of cardiac mechanics was found to lead to a reduction of shear amplitudes, due to an increase of transmural mechanical coupling (6,29,30).Therefore, the aim of the current study was to investigate the effects of a physiological, slightly asynchronous, timing of activation and the effects of triaxial active stress development on myofiber reorientation, on LV global pump and on local myofiber function, and on shear deformation, as computed in a Address for reprint requests and other correspondence: M. Pluijmert, Maastricht Univ., …”
mentioning
confidence: 98%
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