Determinants of Infant Growth in Four Age Windows: A Twin Study

Touwslager, Robbert N.H.; Gielen, Marij; Derom, Cathérine; Mulder, A. L. M.; Gerver, Willem‐Jan M.; Zimmermann, Luc J. I.; Houben, Alfons J.H.M.; Stehouwer, Coen D. A.; Vlietinck, Robert; Loos, Ruth J.F.

doi:10.1016/j.jpeds.2010.10.005

Cited by 21 publications

(16 citation statements)

References 35 publications

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“…This discrepancy was most likely due to low statistical power in the age window from 12 to 24 mo. Nevertheless, the intrapair correlation for growth in this sample was 0.90 in monozygotic twins and 0.48 in dizygotic twins in this age window (29), which suggests a substantial genetic component 1 Results were adjusted for birth weight and gestational age (0-1 and 6-12 mo); sex, birth weight, and gestational age (1-6 mo); and chorionicity, sex, gestational diabetes, and paternal height (12-24 mo). a 2 , c 2 , e 2 , proportion of variance explained by additive genetic (a 2 ), common environmental (c 2 ), and unique environmental factors (e 2 ); ACE, model that contained additive genetic, common environmental, and unique environmental factors; AE, model that contained additive genetic and unique environmental factors; AIC, Akaike's information criterion; CE, model that contained common environmental and unique environmental factors; E, model that contained unique environmental factors; -2LL, -2 log likelihood.…”

Section: Discussionmentioning

confidence: 52%

“…In a previous study in the EFPTS prenatal programming study sample, the following determinants of postnatal growth were identified: birth weight and gestational age (0-1 mo and 6-12 mo); sex, birth weight, and gestational age (0-6 mo); and chorionicity, sex, gestational diabetes, and paternal height (12-24 mo) (29). Therefore, the structural equation modeling analyses in this study were adjusted for these determinants by using determinants from 0 to 6 mo for our analyses from 1 to 6 mo.…”

Section: Discussionmentioning

confidence: 99%

“…These models assume that monozygotic and dizygotic twins share a common environment to the same extent and assume no interaction between genes or between genes and environment. A nonadditive or dominant genetic contribution model was not considered in the current study because the within-pair Pearson correlation coefficient in monozygotic pairs was not more than twice that of dizygotic pairs in a previous study in this study sample (29).…”

Section: Discussionmentioning

confidence: 99%

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Changes in genetic and environmental effects on growth during infancy

Touwslager¹,

Gielen²,

Mulder³

et al. 2011

The American Journal of Clinical Nutrition

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Section: Discussionmentioning

confidence: 52%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

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Changes in genetic and environmental effects on growth during infancy

Touwslager¹,

Gielen²,

Mulder³

et al. 2011

The American Journal of Clinical Nutrition

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“…Normal growth according to Touwslager, et al (2011) is the progression of changes in height, weight and head circumference that are compatible with established standard for a given population. Anthropometric measurement has been defined by Tanner (2001) as the systematic collection and correlation of measurements of certain parameters of the human body in order to assess nutritional status of the individuals and population groups, and as eligibility criteria for nutrition support programmes.…”

Section: Introductionmentioning

confidence: 99%

“…The nutritional status of the child population according to Touwslager, Gielen and Derom (2011) is an important indicator of health and quality of life, reflecting not only the reality of this particular group, but also the society in which they live. Nutrition assessment in the community is essential for accurate planning and implementation of intervention programmes to reduce morbidity and mortality associated with malnutrition (Oninla, Owa, Onayade & Taiwo, 2007).…”

Section: Introductionmentioning

confidence: 99%

Anthropometrically Determined Nutritional Status of Preschool Children in Anambra State, Nigeria

Clementine.¹,

E²,

Ogbonnaya³

et al. 2014

IOSRJNHS

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Heritability of Psychological Traits and Developmental Milestones in Infancy

et al. 2022

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IMPORTANCEAlthough infancy is the most rapid period of postnatal growth and development, factors associated with variation in infant traits are not well understood. OBJECTIVE To synthesize the large twin study literature partitioning phenotypic variance in psychological traits and developmental milestones in infancy into estimates of heritability and shared and nonshared environment. DATA SOURCES PubMed, PsycINFO, and references of included publications were searched up to February 11, 2021. STUDY SELECTION Peer-reviewed publications using the classical twin design to study psychological traits and developmental milestones from birth to 2 years old were included. DATA EXTRACTION AND SYNTHESIS Data were extracted in line with Preferred Reporting Items for Systematic Reviews and Meta-Analyses and categorized using the International Classification of Functioning, Disability and Health: Children and Youth Version. Data were pooled in 3-level random effects models, incorporating within-cohort variance in outcome measurement and between-cohort variance. Data were analyzed from March 2021 through September 2021. MAIN OUTCOMES AND MEASURESThe primary outcomes were monozygotic and dizygotic twin correlations. These were used to calculate genetic and shared and nonshared environment estimates. RESULTSAmong 139 publications that were systematically retrieved, data were available on 79 044 twin pairs (31 053 monozygotic and 47 991 dizygotic pairs), 52 independent samples, and 21 countries. Meta-analyses were conducted on psychological traits and developmental milestones from 106 publications organized into 10 categories of functioning, disability, and health. Moderate to high genetic estimates for 8 categories were found, the highest of which was psychomotor functions (pooled h 2 , 0.59; 95% CI, 0.25-0.79; P < .001). Several categories of traits had substantial shared environment estimates, the highest being mental functions of language (pooled c 2 , 0.59; 95% CI, 0.24-0.86; P = .001). All examined categories of traits had moderate or high nonshared environment estimates, the highest of which were emotional functions (pooled e 2 , 0.42; 95% CI, 0.33-0.50; P < .001) and family relationships (pooled e 2 , 0.42; 95% CI, 0.30-0.55; P < .001).CONCLUSIONS AND RELEVANCE These findings may be an important source of information to guide future gene discovery research, public perspectives on nature and nurture, and clinical insights into the degree to which family history and environments may estimate major domains of infant functioning, disability, and health in psychological traits and developmental milestones.

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Determinants of Infant Growth in Four Age Windows: A Twin Study

Cited by 21 publications

References 35 publications

Changes in genetic and environmental effects on growth during infancy

Changes in genetic and environmental effects on growth during infancy

Anthropometrically Determined Nutritional Status of Preschool Children in Anambra State, Nigeria

Heritability of Psychological Traits and Developmental Milestones in Infancy

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