Determinants of improvement in quality of life of alcohol-dependent patients during an inpatient withdrawal programme

Abstract

Background: To investigate the improvement in quality of life (QoL) of alcohol-dependent patients during a 3-week inpatient withdrawal programme, and to identify the sociodemographic, clinical and alcohol-related variables associated with baseline QoL on admission and with improvement of QoL during residential treatment.Methods: This prospective, observational study included 414 alcohol-dependent patients, hospitalised for a period of 3 weeks. QoL was measured on admission and at discharge using the French version of the Medical Outcome Study SF-36. The mean scores for each dimension and for the Physical and Mental Component Summary scores were calculated.Results: The mean scores per dimension and the mean Physical and Mental Component Summary scores were significantly lower on admission than at discharge; the lowest scores being observed for social functioning and role limitations due to emotional problems. At discharge, the mean scores per dimension were similar to those observed in the French general population. Female gender, age >45 years, living alone, working as a labourer or employee, somatic comorbidity, and the existence of at least five criteria for alcohol dependence according to the DSM-IV classification were associated with a low Physical Component Summary score on admission; psychiatric comorbidity, the presence of at least five DSM-IV dependence criteria, smoking and suicidality were associated with a low Mental Component Summary score on admission. The increase in Physical and Mental Component Summary scores during hospitalisation was more marked when the initial scores were low. Apart from the initial score, the greatest improvement in Physical Component Summary score was seen in patients with a high alcohol intake and in those without a somatic comorbidity; the increase in Mental Component Summary score was greatest in patients without psychotic symptoms and in those who abused or were dependent on illegal drugs.Conclusion: QoL improvement after a residential treatment was related to low QoL scores at admission. Improvement in physical component of QoL was related to baseline alcohol intake and good somatic status. Improvement in mental component of QoL was related to other drugs abuse/dependence.

Effect of exercise on balance performance, gait-speed and quality of life of individuals with substance abuse disorders

“…This means that age of individuals who abuse substance had significant influence on all aspects of their quality of life. This corroborates opinions of previous researchers that substance abuse negatively affects psychiatric symptoms severity as well as quality of life of individuals with mental illness (Foster et al, 1999;Lorenz et al, 2001;Rudolf and Watts, 2002;Morgan et al, 2003;Fassino et al, 2004;Okoro et al, 2004;Vorma et al, 2004;Dalgard et al, 2004;Chen et al, 2006;Costenbader et al, 2007;Urbanoski et al, 2007;Korthuis et al, 2008;Lahmek et al, 2009). The fact that both the educational attainment and occupational status had significant influence on quality of life of individuals who abuse illicit drug in all the domains of WHOQOL-BREF shows that individuals suffering from substance abuse disorder but have higher educational qualification and are employed have a higher quality of life.…”

“…Individuals who abuse elicit substances have an increase risk of negative consequences such as suicide, arrest/incarceration, homelessness, family conflicts, violence and destructive behaviours, victimization, physical health problems and Gbiri et al 93 quality of life (Foster et al, 1999;Lorenz et al, 2001;Rudolf and Watts, 2002;Morgan et al, 2003;Fassino et al, 2004;Okoro et al, 2004;Vorma et al, 2004;Dalgard et al, 2004;Chen et al, 2006;Costenbader et al, 2007;Urbanoski et al, 2007;Korthuis et al, 2008;Lahmek et al, 2009). Some of the most observed physical problems in individuals who abuse illicit substances are balance and gait instability as well as postural disorientation (Torvik and Torp, 1986;Victor et al, 1989;Sullivan et al, 2000a, b;Sullivan et al, 2004;Deshmukh et al, 2002).…”

“…Health-related quality of life is an essential health care indicator for persons who live with chronic illnesses (Foster et al, 1999;Lorenz et al, 2001;Rudolf and Watts, 2002;Morgan et al, 2003;Fassino et al, 2004;Urbanoski et al, 2007;Korthuis et al, 2008;Lahmek et al, 2009). Quality of life measures perceived mental and physical health over a period of time and it is used as an important construct in evaluating health and medical interventions and treatment outcomes (Foster et al, 1999;Lorenz et al, 2001;Rudolf and Watts, 2002;Morgan et al, 2003;Fassino et al, 2004;Okoro et al, 2004;Vorma et al, 2004;Dalgard et al, 2004;Chen et al, 2006;Costenbader et al, 2007;Urbanoski et al, 2007;Korthuis et al, 2008;Lahmek et al, 2009).…”

“…Quality of life measures perceived mental and physical health over a period of time and it is used as an important construct in evaluating health and medical interventions and treatment outcomes (Foster et al, 1999;Lorenz et al, 2001;Rudolf and Watts, 2002;Morgan et al, 2003;Fassino et al, 2004;Okoro et al, 2004;Vorma et al, 2004;Dalgard et al, 2004;Chen et al, 2006;Costenbader et al, 2007;Urbanoski et al, 2007;Korthuis et al, 2008;Lahmek et al, 2009). Many studies have evaluated quality of life in chronic illnesses in Nigeria population with little interest on substance abusers (Akinpelu and Gbiri, 2009;Owolabi, 2010).…”

Alcohol Dependence and The Quality Of Life

“…Alkolü bırakmanın ardından yaşam kalitesinde gelişimler gözlenmiş (12,26) ve bu gelişimin zamanla kararlı bir düzeye geldiği gösterilmiştir (26,27) . Morgan ve ark.…”