Determinants and frequency of pharmaceutical compounding in pharmacy practice in Palestine

Abstract

While most respondent pharmacists provide a compounding service this represents only a small percentage of the total volume of dispensed prescriptions. Most responding physicians do not prescribe medications that require compounding because they lack trust in the quality of the compounded formulations.

Extemporaneous Compounding Practice by Pharmacists: A Systematic Review

“…al noted that the overall frequency of prescriptions for pharmacy-compounded medicine in relation to the total number of prescription was 3.4% [18]. Zaid et al found that 1.55% of pharmacists provided compounding services based on prescriptions requested by doctor [13]. A study by Pappas found that only one-third of physician prescribed extemporaneous product [12].…”

“…Only one study use a random sampling in selected areas [13]. Since data were collected retrospectively, the interpretation of the data may be limited by the documentation available.…”

“…In addition, modification to compounding drugs in the pharmacy may not be captured all in retrospective analysis. Most of the studies were using pharmacists in hospital or community practice as a target of respondents [13,14,17,18]. Two studies are invited hospital pharmacists for data source [11,15].…”

“…Richey et al [11], Pappas et al [12] and Lindbald et al [16] invited physicians served as a respondent for the source of information [11,12]. In regards with types of patient, four studies focusing compounding practice for paediatric patients in the clinics, hospital, and pharmacies [5,15,18] and rest studies used non-classified patients (both adults and children) [7,[12][13][14][16][17][18].…”

“…Five studies used a questionnaire to identify the current practice of compounding [7,[11][12][13][14], with various way of delivering questionnaire include self-administered, face to face interviews [13], or mailed questionnaire. Richey used a combination of questionnaire and direct observation and compared the results of data [11].…”