Determinação dos fatores de recuperação do 111In e do 99mTc na quantificação de atividade com imagens SPECT

Abstract

which significantly improves the image contrast and the detection of small lesions in the patient's body.Many authors have evaluated the accuracy in activity quantification performed with SPECT images by means of experimental studies , but the presented results cannot be compared, as in such studies different reconstruction methods (with different corrections), different activity values and source objects of different shapes and sizes were utilized. However, the results are in agreement with the fact that, because of the partial volume effect, the accuracy in INTRODUCTIONIn nuclear medicine, the quantification of scintigraphic images(1) (e.g.: single photon emission computed tomography -SPECT) is used both for estimating the activity in the body of patients submitted to therapy with internal emitters, and in pharmacokinetic studies for approval of new radiopharmaceutical drugs (2,3) . The SPECT tomography technique allows the visualization of spatial distribution of radioactive material in the structure of interest, as it eliminates data overlap, 0100-3984 © Colégio Brasileiro de Radiologia e Diagnóstico por Imagem