Abstract:The VDBP amino acid sequence is divided into three domains and has 458 amino acids. Exon 11 in domain III has two SNPs, rs7041 and rs4588, each corresponding to one of the major VDBP kinds (VDBP1S, VDBP1F, and VDBP2). Transport of vitamin D3 to the liver and 25(O.H.)D to the kidney, 1,25(O.H.)2D transport to target organs is mediated by vitamin D-binding protein, which interacts with a particular vitamin D receptor (VDR) to explain biological activities. This study aims to determine whether the VDBP gene has t… Show more
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