“…Our previous study found out FAdV-2 can also cause HHS in chicks in both clinical and experimental cases ( Xie et al, 2022 ). Recently, Outbreaks of FAdV-2 has been frequently reported worldwide in chicken flocks, leading to significant economic losses in the poultry industry ( Li et al, 2022 ; Niu et al, 2022 ; Santander-Parra et al, 2023 ; Wang et al, 2023 ; Zhuang et al, 2023 ). FAdV-2 and FAdV-8b have been reported in South Africa ( Joubert et al, 2014 ; Maartens et al, 2014 ), while FAdV-2, -8a, -8b, and -11 were prevalent in Europe and North America ( Schade et al, 2013 ; Marek et al, 2016 ; Niczyporuk, 2016 ; Schachner et al, 2016 ; Niczyporuk and Kozdrun, 2022 ).…”