Detection of Zika Virus in Semen

Atkinson, Barry; Hearn, Pasco; Afrough, Babak; Lumley, Sarah; Carter, Dan; Aarons, Emma; Simpson, Andrew J. H.; Brooks, Timothy; Hewson, Roger

doi:10.3201/eid2205.160107

Cited by 315 publications

(231 citation statements)

References 2 publications

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“…At this time, the length of time that virus might persist in semen is unknown. A recent report described detection of Zika virus RNA in semen by RT-PCR as long as 62 days after illness onset; however, infectious virus was not cultured from semen (9). Recommendations for prevention of sexual transmission of Zika virus will be updated as new information regarding the risks for transmission becomes available.…”

Section: Discussionmentioning

confidence: 99%

Transmission of Zika Virus Through Sexual Contact with Travelers to Areas of Ongoing Transmission — Continental United States, 2016

Hills¹,

Russell²,

Hennessey³

et al. 2016

MMWR Morb. Mortal. Wkly. Rep.

390

234

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Section: Discussionmentioning

confidence: 99%

Transmission of Zika Virus Through Sexual Contact with Travelers to Areas of Ongoing Transmission — Continental United States, 2016

Hills¹,

Russell²,

Hennessey³

et al. 2016

MMWR Morb. Mortal. Wkly. Rep.

390

234

View full text Add to dashboard Cite

“…Still at this point, there is no validated data that suggests the replacement of blood with urine as a sample specimen [20,31,96]. A study has reported the time of stay of ZIKV in the semen of infected men for more than 3 weeks [51], while another study has reported ZIKV RNA in the semen for up to 62 days [97]. ZIKV detection can also be made in other specimens, for example cerebrospinal fluid, placenta and amniotic fluid [14,71].…”

Section: Diagnosis Direct Viral Diagnosismentioning

confidence: 99%

Zika virus disease: a current review of the literature

et al. 2016

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“…Viral load in the semen was 100,000 × higher than in the serum or urine, which can be explained by the immune privilege of male reproductive organs (56) . Viral RNA has been detected in the semen up to 62 days after the onset of illness, making sexual transmission a serious concern unless condom use is encouraged (57) .…”

Section: Zika Virus: Old and Newly Identified Transmission Modesmentioning

confidence: 99%

Zika virus: what do we know about the viral structure, mechanisms of transmission, and neurological outcomes?

Silva

Souza

2016

Rev. Soc. Bras. Med. Trop.

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The Zika virus epidemic that started in Brazil in 2014 has spread to >30 countries and territories in Latin America, leading to a rapid rise in the incidence of microcephalic newborns and adults with neurological complications. At the beginning of the outbreak, little was known about Zika virus morphology, genome structure, modes of transmission, and its potential to cause neurological malformations and disorders. With the advancement of basic science, discoveries of the mechanisms of strain variability, viral transfer to the fetus, and neurovirulence were published. These will certainly lead to the development of strategies to block vertical viral transmission, neuronal invasion, and pathogenesis in the near future. This paper reviews the current literature on Zika virus infections, with the aim of gaining a holistic insight into their etiology and pathogenesis. We discuss Zika virus history and epidemiology in Brazil, viral structure and taxonomy, old and newly identified transmission modes, and neurological consequences of infection.

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Detection of Zika Virus in Semen

Cited by 315 publications

References 2 publications

Transmission of Zika Virus Through Sexual Contact with Travelers to Areas of Ongoing Transmission — Continental United States, 2016

Transmission of Zika Virus Through Sexual Contact with Travelers to Areas of Ongoing Transmission — Continental United States, 2016

Zika virus disease: a current review of the literature

Zika virus: what do we know about the viral structure, mechanisms of transmission, and neurological outcomes?

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