Detection of Taenia hydatigena copro-antigens by ELISA in dogs

Deplazes, Peter; Gottstein, Bruno; Stingelin, Yvonne; Eckert, Johannes

doi:10.1016/0304-4017(90)90097-u

Cited by 54 publications

(41 citation statements)

References 12 publications

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“…No published data provide a reliable estimate of the diagnostic sensitivity and specificity of T. hydatigena egg detection in dog feces. Because proglottids are predominantly shed without defecation, 46 we believe that sensitivity would be much lower than the estimated 62.5% observed for T. solium taeniasis. 38,47 Our prevalence estimates of T. hydatigena were in the order of 5-6% of village dogs and this corresponded to prevalence in pigs of 50-60%.…”

Section: Discussionmentioning

confidence: 82%

A Cross-Sectional Study of Taenia solium in a Multiple Taeniid-Endemic Region Reveals Competition May be Protective

Conlan¹,

Vongxay²,

Khamlome³

et al. 2012

The American Society of Tropical Medicine and Hygiene

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Abstract. We conducted cross-sectional surveys for taeniasis and cysticercosis in humans, pigs, and dogs in four northern provinces of Laos. Human cysticercosis and taeniasis prevalence was 2.2% (95% confidence interval [CI] = 1.4-3.0%) and 8.4% (95% CI = 6.9-9.9%), respectively. Eating uncooked beef, being male, province of residence, age, and ethnicity were significant risk factors for taeniasis and only province of residence was a significant risk factor for cystiercosis. Thirty-five human tapeworms were recovered during the survey and 33 (94.3%) and 2 (5.7%) were identified as Taenia saginata and T. solium, respectively. Maximum-likelihood adjusted prevalence of T. solium and T. hydatigena in pigs was 4.2% (95% CI = 0.5-7.9%) and 55.9% (95% CI = 47.5-64.3%), respectively, and T. hydatigena taeniasis in dogs was 4.8% (95% CI = 0.0 -11.3%). Taenia hydatigena and T. saginata were the most prevalent taeniids in the respective pig and human populations and together may suppress T. solium transmission.

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Section: Discussionmentioning

confidence: 82%

A Cross-Sectional Study of Taenia solium in a Multiple Taeniid-Endemic Region Reveals Competition May be Protective

Conlan¹,

Vongxay²,

Khamlome³

et al. 2012

The American Society of Tropical Medicine and Hygiene

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“…Thus, the time between deworming and sample collection was always considerably longer than the prepatency periods of T. hydatigena (57-71 days, Deplazes et al 1990) or E. granulosus s.l. (34-58 days; Thompson, 2017).…”

Section: Samplingmentioning

confidence: 99%

The impact of socio-cultural factors on transmission of Taenia spp. and Echinococcus granulosus in Kosovo

et al. 2017

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S U M M A R YEchinococcus granulosus sensu latu (s.l.) and Taenia hydatigena are common parasites of ruminant intermediate hosts in the Balkans. Transmission is linked mainly to home slaughtering and the feeding of infected organs to dogs. In Kosovo, many old sheep are slaughtered particularly during Eid al-Adha (Feast of Sacrifice). To determine whether this tradition could affect parasite transmission, we compared the probability of 504 dogs to contract taenid infections after deworming during one period before Eid al-Adha and a similar period beginning with this event. Initially, taeniid eggs were detected in 6·2% (CI 4·2-8·6) of the dogs. The prevalence before Eid al-Adha was significantly lower (1·2%, CI 0·4-2·6) as compared with the prevalence after the event (4·3%, CI 2·6-6·3). A comparable trend was apparent at species level for T. hydatigena and E. granulosus. These results indicate that the pronounced increase of taeniid infections, including E. granulosus s.l., after Eid al-Adha is linked to traditional home slaughtering that occurs during this celebration. This particular epidemiological situation provides an opportunity for implementing focussed control activities.

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“…Alternatives to the coprological or serological diagnosis of adult-stage Echinococcus infections in definitive hosts have been proposed, for example, the antibody sandwich-ELISA (32). Affinity-purified polyclonal antibodies raised against excretory and secretory antigens of adult-stage tapeworms were used to develop an ELISA that permitted the detection of coproantigens from E. granulosus and E. multilocularis in dog or fox fecal samples.…”

Section: Immunodiagnosis In Definitive Hostsmentioning

confidence: 99%

Molecular and immunological diagnosis of echinococcosis

Gottstein

1992

Clin Microbiol Rev

125

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Echinococcosis is an infectious disease of humans caused by the larval (metacestode) stage of the cestode species Echinococcus granulosus (cystic echinococcosis or hydatid disease) or Echinococcus multilocularis (alveolar echinococcosis or alveolar hydatid disease). Clinical manifestations depend primarily on localization and size of hepatic lesions and may include hepatomegaly, obstructive jaundice, or cholangitis. Prognostically, alveolar echinococcosis is considered similar to liver malignancies, including a lethality rate of 90% for untreated cases. Diagnosis is based on imaging techniques coupled with immunodiagnostic procedures. Antibody detection tests for E. multilocularis have markedly improved with the use of affinity-purified Em2 antigen and recombinant antigen II/3-10 in enzyme immunoassays. Antigens of corresponding quality for E. granulosus are still unavailable. The detection of circulating antigens and immune complexes in the sera of patients with cystic echinococcosis, the demonstration of in vitro lymphocyte proliferation in response to stimulation with Echinococcus antigens, and the discrimination of serum immunoglobulin isotype activity to various Echinococcus antigens in both cystic and alveolar echinococcosis have been suggested for diagnostic purposes as well as for monitoring patients after treatment. New diagnostic molecular tools include DNA probes for Southern hybridization tests and polymerase chain reaction for the amplification of E. multilocularis and E. granulosus species-specific DNA fragments.

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Detection of Taenia hydatigena copro-antigens by ELISA in dogs

Cited by 54 publications

References 12 publications

A Cross-Sectional Study of Taenia solium in a Multiple Taeniid-Endemic Region Reveals Competition May be Protective

A Cross-Sectional Study of Taenia solium in a Multiple Taeniid-Endemic Region Reveals Competition May be Protective

The impact of socio-cultural factors on transmission of Taenia spp. and Echinococcus granulosus in Kosovo

Molecular and immunological diagnosis of echinococcosis

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