Detection of soft‐tissue abscess: Comparison of diffusion‐weighted imaging to contrast‐enhanced MRI

Chun, Chang Woo; Jung, Joon-Yong; Baik, Jun Seung; Jee, Won-Hee; Kim, Sun Ki; Shin, Seung Han

doi:10.1002/jmri.25743

Cited by 45 publications

(23 citation statements)

References 39 publications

(78 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Abscesses and thrombi impede the diffusivity of water molecules because they have a hyperviscous nature [30,31]. The median ADC value (0.877 × 10 −3 mm 2 /s) of abscesses was significantly lower than that (2.118 × 10 −3 mm 2 /s) of phlegmon (p < 0.001) and that (3.008 × 10 −3 mm 2 /s) of edema (p < 0.01) [32]. In our article, the ADCs of lung cancers were distributed over 0.9 to 1.6 × 10 −3 mm 2 /s.…”

Section: Discussionmentioning

confidence: 99%

Relationships and Qualitative Evaluation between Diffusion-Weighted Imaging and Pathologic Findings of Resected Lung Cancers

Usuda

Iwai

Yamagata

et al. 2020

Cancers

View full text Add to dashboard Cite

For detecting malignant tumors, diffusion-weighted magnetic resonance imaging (DWI) as well as fluoro-2-deoxy-glucose positron emission tomography/computed tomography (FDG-PET/CT) are available. It is not definitive how DWI correlates the pathological findings of lung cancer. The aim of this study is to evaluate the relationships between DWI findings and pathologic findings. In this study, 226 patients with resected lung cancers were enrolled. DWI was performed on each patient before surgery. There were 167 patients with adenocarcinoma, 44 patients with squamous cell carcinoma, and 15 patients with other cell types. Relationships between the apparent diffusion coefficient (ADC) of DWI and the pathology were analyzed. When the optimal cutoff value (OCV) of ADC for diagnosing malignancy was 1.70 × 10−3 mm2/s, the sensitivity of DWI was 92.0% (208/226). The sensitivity was 33.3% (3/9) in mucinous adenocarcinoma. The ADC value (1.31 ± 0.32 × 10−3 mm2/s) of adenocarcinoma was significantly higher than that (1.17 ± 0.29 × 10−3 mm2/s) of squamous cell carcinoma (p = 0.012), or (0.93 ± 0.14 × 10−3 mm2/s) of small cell carcinoma (p = 0.0095). The ADC value (1.91 ± 0.36 × 10−3 mm2/s) of mucinous adenocarcinoma was significantly higher than that (1.25 ± 0.25 × 10−3 mm2/s) of adenocarcinoma with mucin and that (1.24 ± 0.30 × 10−3 mm2/s) of other cell types. The ADC (1.11 ± 0.26 × 10−3 mm2/s) of lung cancer with necrosis was significantly lower than that (1.32 ± 0.33 × 10−3 mm2/s) of lung cancer without necrosis. The ADC of mucinous adenocarcinoma was significantly higher than those of adenocarcinoma of other cell types. The ADC of lung cancer was likely to decrease according to cell differentiation decreasing. The sensitivity of DWI for lung cancer was 92% and this result shows that DWI is valuable for the evaluation of lung cancer. Lung cancer could be evaluated qualitatively using DWI.

show abstract

Section: Discussionmentioning

confidence: 99%

Relationships and Qualitative Evaluation between Diffusion-Weighted Imaging and Pathologic Findings of Resected Lung Cancers

Usuda

Iwai

Yamagata

et al. 2020

Cancers

View full text Add to dashboard Cite

show abstract

“…Some pathologic processes such as pulmonary tuberculosis, nontuberculous mycobacteria, pulmonary abscesses, sarcoidosis, chronic pneumonia, scars, and other inflammatory or infectious conditions behave like malignant lesions by exhibiting diffusion restriction [ 19 , 20 , 21 ]. ADC values of abscesses are low, and it was mentioned that median ADC value (0.877 × 10 −3 mm 2 /s) of abscesses was significantly lower than that (2.118 × 10 −3 mm 2 /s) of phlegmon ( p < 0.001), and that (3.008 × 10 −3 mm 2 /s) of edema ( p < 0.01) [ 22 ]. There were several reasons for the restricted diffusion of PAMI.…”

Section: Discussionmentioning

confidence: 99%

Whole-Lesion Apparent Diffusion Coefficient Histogram Analysis: Significance for Discriminating Lung Cancer from Pulmonary Abscess and Mycobacterial Infection

Usuda

Iwai

Yamagata

et al. 2021

Cancers

View full text Add to dashboard Cite

Diffusion-weighted magnetic resonance imaging (DWI) can differentiate malignant from benign pulmonary nodules. However, it is difficult to differentiate pulmonary abscesses and mycobacterial infections (PAMIs) from lung cancers because PAMIs show restricted diffusion in DWI. The study purpose is to establish the role of ADC histogram for differentiating lung cancer from PAMI. There were 41 lung cancers (25 adenocarcinomas, 16 squamous cell carcinomas), and 19 PAMIs (9 pulmonary abscesses, 10 mycobacterial infections). Parameters more than 60% of the area under the ROC curve (AUC) were ADC, maximal ADC, mean ADC, median ADC, most frequency ADC, kurtosis of ADC, and volume of lesion. There were significant differences between lung cancer and PAMI in ADC, mean ADC, median ADC, and most frequency ADC. The ADC (1.19 ± 0.29 × 10−3 mm2/s) of lung cancer obtained from a single slice was significantly lower than that (1.44 ± 0.54) of PAMI (p = 0.0262). In contrast, mean, median, or most frequency ADC of lung cancer which was obtained in the ADC histogram was significantly higher than the value of each parameter of PAMI. ADC histogram could discriminate PAMIs from lung cancers by showing that AUCs of several parameters were more than 60%, and that several parameters of ADC of PAMI were significantly lower than those of lung cancer. ADC histogram has the potential to be a valuable tool to differentiate PAMI from lung cancer.

show abstract

“…However, contrast-enhanced images are extremely helpful for specific diagnostic tasks, such as delineating a necrotic, non-enhancing bone, or rim enhancing fluid collections, such as abscess and sinus tract. Diffusion-weighted imaging helps in characterizing fluid collections and adds certainty in the diagnosis of abscess, which can be particularly useful in patients with contraindications to intravenous gadolinium based contrast [93,94]. Diagnosis of the osteomyelitis in a setting of neuropathic arthropathy is particularly challenging.…”

Section: Pedal Infectionmentioning

confidence: 99%

Magnetic resonance imaging of the ankle and foot

Gorbachova¹

2020

Pol J Radiol

View full text Add to dashboard Cite

This article reviews the magnetic resonance imaging (MRI) findings of the normal anatomy and various pathologic conditions of the ankle and foot commonly encountered in clinical practice. The spectrum of entities discussed includes osseous and osteochondral injuries, ligamentous injuries, common traumatic and degenerative tendon pathology, abnormalities of transverse tarsal joint (Chopart) and tarsometatarsal joint (Lisfranc) complexes, pathological conditions affecting capsuloligamentous structures of the great toe and lesser toes, as well as pedal infection, with a focus on diabetic osteomyelitis and neuropathic osteoarthropathy.

show abstract

Detection of soft‐tissue abscess: Comparison of diffusion‐weighted imaging to contrast‐enhanced MRI

Cited by 45 publications

References 39 publications

Relationships and Qualitative Evaluation between Diffusion-Weighted Imaging and Pathologic Findings of Resected Lung Cancers

Relationships and Qualitative Evaluation between Diffusion-Weighted Imaging and Pathologic Findings of Resected Lung Cancers

Whole-Lesion Apparent Diffusion Coefficient Histogram Analysis: Significance for Discriminating Lung Cancer from Pulmonary Abscess and Mycobacterial Infection

Magnetic resonance imaging of the ankle and foot

Contact Info

Product

Resources

About