Detection of Short-Term Side Effects of ChAdOx1 nCoV-19 Vaccine: A Cross-Sectional Study in a War-Torn Country

Abstract

The chAdOx1 nCoV-19 vaccine is the first COVID-19 vaccine available in Yemen. Hence, this local-based study was used to identify the type and frequency of short-term side effects following 48 hours of the first shot of the vaccine. Methods: A cross-section of vaccinated participants in Aden were surveyed by telephone. Descriptive statistics were used for statistical analysis. Results: A total of 500 participants were included through convenient sampling. 27% of them were health care providers. Nearly 70% of the respondent experienced side effects. The top three side effects reported were fever (n=276, 55.2%), myalgia (n=270, 54%) and fatigue (n=247, 49.4%). Generally, most participants stated that they experienced the side effects after the first 24 hours of vaccination. Conclusion: Side effects that participants experienced were not different from the literature, indicating a safe profile for the vaccine. Further studies are needed to identify the side effects after the second and third dose of the vaccine. In addition, more studies are required to assess the efficacy of the existing vaccines against new variants.

Insights into participation in ward rounds in hospitals: A survey of clinical pharmacists' perceptions

“…Clinical pharmacists’ participation in hospital wards has led to improved clinical outcomes for patients with various diseases, including chronic non-communicable and infectious diseases ( Campbell et al, 2023 ; Thomas et al, 2014; Bullock et al, 2020 ; Kubas et al, 2020 ). Recently, this was clearly supported by their participation during the COVID-19 pandemic and the critical role they played ( Baudouin et al, 2023 ; Alshakka et al, 2022 ). Hence, we sincerely believe that the longer internship duration may have provided these clinical pharmacists with more opportunities to participate in multidisciplinary team discussions actively, contribute to treatment plans, and see the positive impact of their interventions.…”

Exploring knowledge, attitudes and practice toward medication therapy management services among pharmacists in Yemen

“…Our results show that about 10% of the respondents "all times" or "most of the time" "monitor and evaluate the patient's response to therapy, including safety and effectiveness" and while only 11% of them were "Performing a comprehensive medication review to identify, resolve, and prevent medication-related problems, including adverse drug events". This is despite substantial evidence supporting its effectiveness in enhancing clinical outcomes, preventing adverse drug reactions, and reducing costs across various medical conditions [12,24,28]. Documentation of the care delivered to patients and the ability to communicate effectively is essential for assessing their impact on patient outcomes.…”

“…MTM allows pharmacists to engage in the treatment and management of patient cases [10]. As a consequence, they can identify additional DRPs, encourage rational drug usage, and assure medical safety and efficacy, particularly in older adults with comorbidities and multiple medications [3,11,12]. Furthermore, expert prescription recommendations offered by pharmacists will raise patients' understanding of medications, enhance adherence, and lower the financial burden [13][14][15].…”

Yemeni university students public perceptions toward the use of artificial intelligence in healthcare: A cross-sectional study

“…The exploration of public perceptions regarding the use of AI in healthcare holds particular significance. Yemen faces unique challenges in healthcare accessibility and resources, exacerbated by ongoing civil conflict and humanitarian crises [13,14]. Investigating the perceptions of individuals in this context provides a crucial lens through which to understand how a population coping with limited access to medical resources perceives the potential of AI to address healthcare challenges.…”