Detection of schistosomiasis cases in low-transmission areas based on coprologic and serologic criteria

Noya, Belkisyolé Alarcón de; Ruiz, Rosana Figueroa; Losada, Sandra; Colmenares, Cecilia; Contreras, Rosa; Cesari, Italo M.; Noya, Óscar

doi:10.1016/j.actatropica.2007.04.018

Cited by 50 publications

(33 citation statements)

References 25 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Immunological methods are particularly useful in cases where parasitological tests are negative for individuals with light infections (92). The development of immunological diagnosis has paved the way for less laborious rapid tests that are useful both in communities in areas of endemicity and at point-of-care facilities.…”

Section: Immunological Diagnosismentioning

confidence: 99%

“…The test has a high sensitivity and specificity (108), and it has been used for diagnosis, mainly for S. japonicum infection in China, and as a reference for comparison with other procedures (109,110). It has also been combined with copro-microscopy to improve diagnostic accuracy (92,111). Major drawbacks associated with the COPT are its labor-intensiveness, its rather complex and lengthy procedure, and the long gap in seroconversion following treatment, which can result in the misdiagnosis of a cleared infection (45,92).…”

Section: Antibody Detectionmentioning

confidence: 99%

“…It has also been combined with copro-microscopy to improve diagnostic accuracy (92,111). Major drawbacks associated with the COPT are its labor-intensiveness, its rather complex and lengthy procedure, and the long gap in seroconversion following treatment, which can result in the misdiagnosis of a cleared infection (45,92). This becomes important in the evaluation of schistosomiasis control programs involving mass drug administration with PZQ.…”

Section: Antibody Detectionmentioning

confidence: 99%

See 2 more Smart Citations

Advances in the Diagnosis of Human Schistosomiasis

et al. 2015

View full text Add to dashboard Cite

SUMMARY Schistosomiasis is a major neglected tropical disease that afflicts more than 240 million people, including many children and young adults, in the tropics and subtropics. The disease is characterized by chronic infections with significant residual morbidity and is of considerable public health importance, with substantial socioeconomic impacts on impoverished communities. Morbidity reduction and eventual elimination through integrated intervention measures are the focuses of current schistosomiasis control programs. Precise diagnosis of schistosome infections, in both mammalian and snail intermediate hosts, will play a pivotal role in achieving these goals. Nevertheless, despite extensive efforts over several decades, the search for sensitive and specific diagnostics for schistosomiasis is ongoing. Here we review the area, paying attention to earlier approaches but emphasizing recent developments in the search for new diagnostics for schistosomiasis with practical applications in the research laboratory, the clinic, and the field. Careful and rigorous validation of these assays and their cost-effectiveness will be needed, however, prior to their adoption in support of policy decisions for national public health programs aimed at the control and elimination of schistosomiasis.

show abstract

Section: Immunological Diagnosismentioning

confidence: 99%

Section: Antibody Detectionmentioning

confidence: 99%

Section: Antibody Detectionmentioning

confidence: 99%

See 1 more Smart Citation

Advances in the Diagnosis of Human Schistosomiasis

et al. 2015

View full text Add to dashboard Cite

show abstract

“…A sensitive test is also important to monitor for emerging drug resistance and in efficacy trials comparing different anthelmintic drugs or regimens. Finally, as highlighted for schistosomiasis, low-intensity infection in low-transmission areas may be responsible for persistence of transmission of the disease, hamper its eradication (1), and continue to cause chronic diseases.…”

Section: Laboratory Procedures To Develop the Pcr Tests (I)mentioning

confidence: 99%

PCR Diagnosis of Opisthorchis viverrini and Haplorchis taichui Infections in a Lao Community in an Area of Endemicity and Comparison of Diagnostic Methods for Parasitological Field Surveys

et al. 2009

View full text Add to dashboard Cite

show abstract

“…The few schistosomiasis seroprevalence studies that exist indicate that 90% of those living in high-risk areas will acquire an infection at some point in their lives, which often occurs before the age of ten. In low-risk areas, between 25% to 40% will be infected by the age of 35 [18, 19]. Fragile health systems coupled with lack of safe water, sanitation, and hygiene in many areas throughout Africa make schistosomiasis particularly challenging to control [20].…”

Section: Introductionmentioning

confidence: 99%

Interaction between Salmonella and Schistosomiasis: A Review

Hsiao¹,

Toy²,

Seo³

et al. 2016

PLoS Pathog

View full text Add to dashboard Cite

The interaction between schistosomiasis and Salmonella is a particularly important issue in Africa, where dual infection by the parasite and the bacterium are likely common. In this review, the ways in which schistosomiasis affects human biology as it relates to Salmonella are described. Those who are infected by both organisms experience reduced immunological functioning, exhibit irreversible organ damage due to prolonged schistosomiasis infection, and become latent carriers of Salmonella enterica serotypes Typhi and Paratyphi and S. Typhimurium. The sequestration of the bacteria in the parasite leads to ineffective antibiotic treatment because the bacteria cannot be completely killed, and lingering infection may then lead to antimicrobial resistance. These manifestations are likely not just for those dually infected but also for those first infected with schistosomes and, later, Salmonella. More data are needed to better understand dual infection, particularly as it may impact treatment and prevention of schistosomiasis and Salmonella in sub-Saharan Africa.

show abstract

Detection of schistosomiasis cases in low-transmission areas based on coprologic and serologic criteria

Cited by 50 publications

References 25 publications

Advances in the Diagnosis of Human Schistosomiasis

Advances in the Diagnosis of Human Schistosomiasis

PCR Diagnosis of Opisthorchis viverrini and Haplorchis taichui Infections in a Lao Community in an Area of Endemicity and Comparison of Diagnostic Methods for Parasitological Field Surveys

Interaction between Salmonella and Schistosomiasis: A Review

Contact Info

Product

Resources

About