Detection of ricin by using gold nanoclusters functionalized with chicken egg white proteins as sensing probes

Selvaprakash, Karuppuchamy; Chen, Yu-Chie

doi:10.1016/j.bios.2016.10.086

Cited by 42 publications

(14 citation statements)

References 49 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In fact, documented events confirm its use in bioterrorist attacks. In literature, a detection method based on the application of gold nanoclusters (AuNCs@ew) is reported [143,164]. In this assay, the authors used AuNCs nanoparticles functionalized with chicken ovalbumin, that are able to recognize ricin.…”

Section: Securitymentioning

confidence: 99%

Emergent Biosensing Technologies Based on Fluorescence Spectroscopy and Surface Plasmon Resonance

Camarca

Varriale

Capo

et al. 2021

Sensors

View full text Add to dashboard Cite

The purpose of this work is to provide an exhaustive overview of the emerging biosensor technologies for the detection of analytes of interest for food, environment, security, and health. Over the years, biosensors have acquired increasing importance in a wide range of applications due to synergistic studies of various scientific disciplines, determining their great commercial potential and revealing how nanotechnology and biotechnology can be strictly connected. In the present scenario, biosensors have increased their detection limit and sensitivity unthinkable until a few years ago. The most widely used biosensors are optical-based devices such as surface plasmon resonance (SPR)-based biosensors and fluorescence-based biosensors. Here, we will review them by highlighting how the progress in their design and development could impact our daily life.

show abstract

Section: Securitymentioning

confidence: 99%

Emergent Biosensing Technologies Based on Fluorescence Spectroscopy and Surface Plasmon Resonance

Camarca

Varriale

Capo

et al. 2021

Sensors

View full text Add to dashboard Cite

show abstract

“…Due to the presence of the Galβ(1 → 4) GlcNAc ligand on egg white, ricin B can be recognized. The main advantages of this method include good selectivity, a low detection limit, and low cost 113 …”

Section: Application To Biomaterialsmentioning

confidence: 99%

“…The main advantages of this method include good selectivity, a low detection limit, and low cost. 113 Using microwave-assisted synthesis to manufacture another egg white-protected gold nanocluster (egg white-AuNCs) as a fluorescent sensor for detecting Hg 2+ and melamine plays an important role in monitoring environmental, biological, and food safety. 114 The physically cross-linked egg white hydrogel has super ductility and self-healing properties and can be used directly in 3D printing, thus providing new insights into the preparation of biosensors.…”

Section: Biosensormentioning

confidence: 99%

An insight on egg white: From most common functional food to biomaterial application

Dong

Zhang

2020

J Biomed Mater Res

View full text Add to dashboard Cite

Natural egg white tis widely used as an ingredient in nutritional foods and for food processing. Due to its characteristic foaming, emulsification, adhesion, and gelation, and its heat setting, biocompatibility, and low cost, research into the application and development of egg white in biomaterials, especially medical biomaterials, have been receiving attention. The composition and characteristics of egg white protein, and the physical mixing and chemically cross‐linking of egg white with other materials used to make degradable packaging films, bioceramics, bioplastics, biomimetic films, hydrogels, 3D scaffolds, bone regeneration, biopatterning, biosensors, and so forth, are reviewed in detail in this report. The novel egg white‐based biomaterials in various forms and applications could be constructed mostly through physical treatments such as ultrasonic wave, ultraviolet, laser and other radiation or high‐temperature calcination. Furthermore, the application and prospects for the use of egg white in biomaterials is also discussed.

show abstract

“…In recent years, a large number of protein-sensing methods based on functionalized fluorescent AuNCs have been developed [101][102][103][104][105][106][107][108][109]. These sensors possess both superior selectivity to target proteins and exceptional optical properties.…”

Section: Detection Of Proteinsmentioning

confidence: 99%

Fluorescent Gold Nanoclusters: Promising Fluorescent Probes for Sensors and Bioimaging

Wang

Zhu

2017

J. Anal. Test.

View full text Add to dashboard Cite

Fluorescent gold nanoclusters (AuNCs) have recently emerged as a novel kind of promising fluorescent probes for high-performance sensors and bioimaging because of their ultrasmall size (\3 nm), strong luminescence, good photostability, and excellent biocompatibility. Over the past decade, we have witnessed growing popularity of AuNCs in analytical applications and enormous efforts have been devoted to their development. In this review, we provide an update on recent advances in the development of AuNCs in terms of physicochemical properties, synthesis strategies, and bioapplications. The optical, electrochemical, catalytical, and solvatochromic properties of AuNCs are first summarized, which are followed by different ligands or template-assisted controllable synthetic methods. Afterwards functionalization of AuNCs is described in terms of ligand exchange, bioconjugation, and noncovalent interaction. We then focus on the applications of AuNCs as fluorescent probes for detection of metal ions, inorganic anions, small biomolecules, proteins, nucleic acids, drug molecules, pH, and temperature. We also summarize the usage of metal NCs in cellular and in vivo targeting and imaging. Finally, we conclude with a brief look at the future challenges and prospects of the development of AuNCs.

show abstract

Detection of ricin by using gold nanoclusters functionalized with chicken egg white proteins as sensing probes

Cited by 42 publications

References 49 publications

Emergent Biosensing Technologies Based on Fluorescence Spectroscopy and Surface Plasmon Resonance

Emergent Biosensing Technologies Based on Fluorescence Spectroscopy and Surface Plasmon Resonance

An insight on egg white: From most common functional food to biomaterial application

Fluorescent Gold Nanoclusters: Promising Fluorescent Probes for Sensors and Bioimaging

Contact Info

Product

Resources

About