Detection of Renal Masses: Sensitivities and Specificities of Excretory Urography/Linear Tomography, US, and CT

Warshauer, David M.; McCarthy, Shirley; Street, L.; Bookbinder, Michael J.; Glickman, Morton G.; Richter, Joan O.; Hammers, Lynwood; Taylor, Caroline; Rosenfield, Arthur T.

doi:10.1016/s0022-5347(17)41103-7

Cited by 8 publications

(7 citation statements)

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“…The clinical suspicion was confirmed by ultrasound, that has an 85% sensitivity in detecting renal masses greater than 3 cm, which is equal to that of IVP with tomography; for lesions of at least 2 cm but smaller than 3 cm, ultrasound is more sensitive than IVP (82% vs 52%) (16).…”

Section: Discussionmentioning

confidence: 92%

Chromophobe renal cell carcinoma in pregnancy: case report and review of the literature

Mancuso¹,

Macrì²,

Palmara³

et al. 2001

SOBS

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Renal cell carcinoma (RCC), particularly the chromophobe type, is a rare pathology in fertile age and consequently, in literature, few cases during pregnancy have been reported.In pregnant women, staging and treatment are uncertain and the diagnosis is often carried out during an ultrasonography performed to check pregnancy. Case reportA 25-years old gravida 2, para 1001, came to our clinic in November 1998 at 10 weeks' gestation because of a palpable mass in her left flank.Laboratory tests were normal and hematuria was not present. A sonogram, performed at admission, showed a 145¿137 mm complex mass under the spleen that prevented the study of the left kidney; annex and embryo (CRL 20 mm) were normal.Magnetic resonance imaging (T1-weighted with fat suppression) showed the presence of a 140¿180¿150 mm homogeneous mass, with clear outline, infiltrating the left kidney and displacing upward, without infiltration, the tail of pancreas (Fig. 1); no metastasis was demonstrated.The patient was transferred to the general surgical department and submitted to left radical nephrectomy with lymphadenectomy.At macroscopic examination (Fig. 2) the volume of left kidney appeared remarkably enlarged (180¿140 mm), with irregular surface, some hemorrhagic areas and solid consistency to the knife.The histological examination (Figs. 3, 4), performed on 5 micron sections included in paraffin and hematoxylin-eosin staining, demonstrated a compact architecture with poligonal cells of variable dimensions with evident cytoplasmatic mem- Abbreviations:RCC: renal cell carcinoma; CRL: crown rump length; IVP: intravenous pyelogram; MRI: magnetic resonance imaging.C Acta Obstet Gynecol Scand 80 (2001) brane, medium width with central or lightly eccentric nuclei, finely granulate chromatine, nucleoli of small and medium dimensions, cytoplasmatic granula in prevalence eosinophilic and rare cells with clear cytoplasm. A modest cellular polymorphism and a moderate vascular congestion were observed.The histologic diagnosis was chromophobe renal carcinoma, eosinophilic variety, grade 1-2 sec. Fuhrman; no evidence of lymphonodal metastasis.The post-operative period was normal and the patient was discharged on 8th post-operative day.The pregnancy wasn't further complicated and the patient in Fig. 1. Preoperative magnetic resonance.Fig. 2. Macroscopic appearance of left kidney.

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Section: Discussionmentioning

confidence: 92%

Chromophobe renal cell carcinoma in pregnancy: case report and review of the literature

Mancuso¹,

Macrì²,

Palmara³

et al. 2001

SOBS

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“…Diagnostic imaging of renal masses has evolved beyond intravenous urography and angiography. Although these techniques remain useful in initial screening for hematuria, ultrasonography and dynamic intravenous contrast-enhanced CT are more accurate in detecting and characterizing renal masses in adults [6,7]. In children, the differential diagnosis is relatively restricted, and many clinics proceed to nephrectomy on the basis of ultrasonographic findings alone (G.J.…”

Section: Discussionmentioning

confidence: 99%

Nephroblastoma in the adult

Marco¹,

Pollera²,

Cognetti³

1999

Med. Pediatr. Oncol.

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“…The sensitivity of excretory urography is only 21%, 52%, and 85% for detecting mass es confirmed and characterized by CT as measuring less than 2 cm, 2-3 cm, and great er than 3 cm, respectively [6]. For the detec tion of TCC, CT urography also compares fa vorably with retrograde pyelography, which enables better urothelial opacification than excretory urography [11].…”

Section: Imaging Strategiesmentioning

confidence: 99%

“…The prevalence of carcinoma among pa tients with macroscopic hematuria attending a hematuria clinic has been reported to be as high as 19% but more typically ranges be tween 3% and 6% [5,6]. Therefore, patients with macroscopic hematuria require com plete evaluation of the upper and lower uri nary tracts with upper urinary tract imaging and cystoscopy to exclude neoplasia.…”

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confidence: 99%

Imaging of Hematuria

O’Connor

Fitzgerald

Maher

2010

American Journal of Roentgenology

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Conventional radiography has no role in the detection of renal or urothelial carcinoma. Low-dose CT offers much greater sensitivities for the detection of urinary tract calculi than radiography at doses equivalent to conventional radiography. Ultrasound alone is insufficient for imaging of hematuria. Using ultrasound alone, it is often difficult to differentiate renal transitional cell carcinoma from other causes of filling defects of the renal collecting system such as blood clots, sloughed papillae, or fungus balls. The prominence of the role of excretory urography in the evaluation of patients with hematuria has diminished, and MDCT urography is now preferred to excretory urography in most cases.

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Detection of Renal Masses: Sensitivities and Specificities of Excretory Urography/Linear Tomography, US, and CT

Cited by 8 publications

References 0 publications

Chromophobe renal cell carcinoma in pregnancy: case report and review of the literature

Chromophobe renal cell carcinoma in pregnancy: case report and review of the literature

Nephroblastoma in the adult

Imaging of Hematuria

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